Technologist in Molecular Biology - MB

Obtain certification and advance your career in molecular biology with our specialized credential.

Uses molecular diagnostic methods to detect and characterize acquired and inherited diseases, including malignant, metabolic, and infectious diseases. Uses advanced techniques, including sequencing and genomic analysis, with applications in personalized medicine.

ASCP and ASCPi Pathways

Attaining an American Society for Clinical Pathology Board of Certification (ASCP BOC) credential requires a laboratory professional or other expert to meet specific education, training, and/or experience standards and to successfully pass an examination demonstrating knowledge and applied skills. The ASCP BOC offers ASCP and ASCPi credentials based on distinct eligibility requirements. All candidates must carefully compare credentialing options. Additional information is available about the similarities and differences between similarities and differences between ASCP and ASCPi credentials and ASCPi credentials.

Eligibility Routes

Each credential has specific eligibility requirements, which are different for ASCP and ASCPi. It’s your responsibility to confirm that your education, training, and/or experience meet the criteria. Submit the correct documentation with your application. Once submitted, the category and route of application cannot be changed.

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Technologist in Molecular Biology - MB(ASCP)

An applicant must be able to verify that they meet all eligibility requirements, including education, training, and/or experience. For complete information, see the Documentation section of the website. 

Education does not need to be from the United States. Details are available by reviewing the webpage titled Acceptable Education, also available in the routes below. 

To be eligible for this examination category, an applicant must satisfy the minimum requirements (for degrees, the stated degree or higher) of at least one of the following routes:

An applicant must be able to verify that they meet all eligibility requirements, including education, training, and/or experience. For complete information, see the  Documentation section of the website. 

Education needs to be equivalent to education from the United States. Details are available by reviewing the webpage titled  Acceptable Education, also available in the routes below. 

To be eligible for this examination category, an applicant must satisfy the minimum requirements (for degrees, the stated degree or higher) of at least one of the following routes: 

    • Baccalaureate degree from an accredited (regionally or nationally) college/university,
    • AND successful completion of a NAACLS-accredited diagnostic molecular science program within the last 5 years. 

      The education received from a NAACLS-accredited diagnostic molecular science program is acceptable for a period of 5 years from the date of completion of that program.
    • Baccalaureate degree from an accredited (regionally or nationally) college/university with a major in biological science or chemistry, OR a baccalaureate degree from an accredited (regionally or nationally) college/university with a combination of 30 semester hours (45 quarter hours) in biology and chemistry, which may be obtained within, or in addition to, the baccalaureate degree, 
    • AND 1 year of full-time acceptable clinical* experience in a molecular biology laboratory^ within the last 5 years, OR 1 year of full-time acceptable veterinary, industry or research experience in a molecular biology laboratory^ in the U.S. or Canada within the last 5 years that must be documented on this Experience Documentation Form.

    *Acceptable Clinical Laboratory:
    CMS CLIA certificate of registration, compliance, accreditation;
    OR DoD CLIP certificate of registration, compliance, accreditation;
    OR JCI accreditation;
    OR Accreditation under ISO 15189.

    ^A molecular biology laboratory is defined as one capable of providing individuals with knowledge and practical experience in all aspects of molecular methods including, but not limited to, nucleic acid isolation, amplification, detection, sequencing, hybridization techniques, and data analysis.

    Experience

    To fulfill the experience requirement for the Technologist in Molecular Biology examination, you must have laboratory experience within the time frame required in at least one of the following areas:

    • Genetics/Genomics (e.g., genotyping, genetic disorders, pharmacogenomics, genome-wide analysis)
    • Oncology (e.g., hematologic lymphoid neoplasms/neoplasia, solid tumor gene markers)
    • Infectious Disease (e.g., molecular microbiology/virology, molecular epidemiology)
    • Molecular Identity Testing (e.g., engraftment, paternity)
    • Clinical laboratory test interpretation and reporting (e.g., genetics/genomics, oncology, histocompatibility, infectious disease, or molecular identity testing)
    • Master’s degree from an accredited (regionally or nationally) college/university in molecular biology, biotechnology, chemistry, biology, immunology, microbiology, allied health, medical laboratory science, or an appropriately related field,
    • AND 6 months of full-time acceptable clinical* experience in a molecular biology laboratory^ within the last 5 years, OR 6 months of full-time acceptable veterinary, industry or research experience in a molecular biology laboratory^ in the U.S. or Canada within the last 5 years that must be documented on this Experience Documentation Form.

    *Acceptable Clinical Laboratory:
    CMS CLIA certificate of registration, compliance, accreditation;
    OR DoD CLIP certificate of registration, compliance, accreditation;
    OR JCI accreditation;
    OR Accreditation under ISO 15189.

    ^A molecular biology laboratory is defined as one capable of providing individuals with knowledge and practical experience in all aspects of molecular methods including, but not limited to, nucleic acid isolation, amplification, detection, sequencing, hybridization techniques, and data analysis.

    Experience

    To fulfill the experience requirement for the Technologist in Molecular Biology examination, you must have laboratory experience within the time frame required in at least one of the following areas:

    • Genetics/Genomics (e.g., genotyping, genetic disorders, pharmacogenomics, genome-wide analysis)
    • Oncology (e.g., hematologic lymphoid neoplasms/neoplasia, solid tumor gene markers)
    • Infectious Disease (e.g., molecular microbiology/virology, molecular epidemiology)
    • Molecular Identity Testing (e.g., engraftment, paternity)
    • Clinical laboratory test interpretation and reporting (e.g., genetics/genomics, oncology, histocompatibility, infectious disease, or molecular identity testing)

  • *Accredited/approved by a governing regulatory association or Ministry. Countries without a prevalent system of accreditation/approval must have programs/educational institutions approved by an International Advisory Board appointed by the ASCP Board of Certification, or eligibility will be determined by an acceptable transcript evaluation. The foreign degree must be equivalent to a U.S. degree.


  • *Accredited/approved by a governing regulatory association or Ministry. Countries without a prevalent system of accreditation/approval must have programs/educational institutions approved by an International Advisory Board appointed by the ASCP Board of Certification, or eligibility will be determined by an acceptable transcript evaluation. The foreign degree must be equivalent to a U.S. degree.


  • *Accredited/approved by a governing regulatory association or Ministry. Countries without a prevalent system of accreditation/approval must have programs/educational institutions approved by an International Advisory Board appointed by the ASCP Board of Certification, or eligibility will be determined by an acceptable transcript evaluation. The foreign degree must be equivalent to a U.S. degree.

    $Degrees/Diplomas in Medical Laboratory Science include Medical Laboratory Science, Medical Technology, Clinical Laboratory Science, and Biomedical Laboratory Science.


  • *Accredited/approved by a governing regulatory association or Ministry. Countries without a prevalent system of accreditation/approval must have programs/educational institutions approved by an International Advisory Board appointed by the ASCP Board of Certification, or eligibility will be determined by an acceptable transcript evaluation. The foreign degree must be equivalent to a U.S. degree.

    #Clinical laboratory accredited by JCI, CAP, under ISO 15189 or authorized by a governing regulatory association or Ministry. Countries without a prevalent system of accreditation must have laboratories approved by an International Advisory Board appointed by the ASCP Board of Certification.

    ^A molecular biology laboratory is defined as one capable of providing individuals with knowledge and practical experience in all aspects of molecular methods including, but not limited to, nucleic acid isolation, amplification, detection, sequencing, hybridization techniques, and data analysis.

    Experience

    To fulfill the experience requirement for the Technologist in Molecular Biology examination, you must have laboratory experience within the time frame required in at least one of the following areas:

    • Genetics/Genomics (e.g., genotyping, genetic disorders, pharmacogenomics, genome-wide analysis)
    • Oncology (e.g., hematologic lymphoid neoplasms/neoplasia, solid tumor gene markers)
    • Infectious Disease (e.g., molecular microbiology/virology, molecular epidemiology)
    • Molecular Identity Testing (e.g., engraftment, paternity)
    • Clinical laboratory test interpretation and reporting (e.g., genetics/genomics, oncology, histocompatibility, infectious disease, or molecular identity testing)
    • Master’s degree from an  accredited/approved* educational institution in molecular biology, chemistry, biology, immunology, microbiology, medical laboratory science$, or an appropriately related field,  

    • AND 6 months of acceptable clinical# experience in a molecular biology laboratory^ that must be documented on this Experience Documentation Form OR 6 months of acceptable veterinary, industry, or research experience in a molecular biology laboratory^ that must be documented on this Experience Documentation Form


    *Accredited/approved by a governing regulatory association or Ministry. Countries without a prevalent system of accreditation/approval must have programs/educational institutions approved by an International Advisory Board appointed by the ASCP Board of Certification, or eligibility will be determined by an acceptable transcript evaluation. The foreign degree must be equivalent to a U.S. degree.

    $Degrees/Diplomas in Medical Laboratory Science include Medical Laboratory Science, Medical Technology, Clinical Laboratory Science, and Biomedical Laboratory Science.

    #Clinical laboratory accredited by JCI, CAP, under ISO 15189 or authorized by a governing regulatory association or Ministry. Countries without a prevalent system of accreditation must have laboratories approved by an International Advisory Board appointed by the ASCP Board of Certification.

    ^A molecular biology laboratory is defined as one capable of providing individuals with knowledge and practical experience in all aspects of molecular methods including, but not limited to, nucleic acid isolation, amplification, detection, sequencing, hybridization techniques, and data analysis.

    Experience

    To fulfill the experience requirement for the Technologist in Molecular Biology examination, you must have laboratory experience within the time frame required in at least one of the following areas:

    • Genetics/Genomics (e.g., genotyping, genetic disorders, pharmacogenomics, genome-wide analysis)
    • Oncology (e.g., hematologic lymphoid neoplasms/neoplasia, solid tumor gene markers)
    • Infectious Disease (e.g., molecular microbiology/virology, molecular epidemiology)
    • Molecular Identity Testing (e.g., engraftment, paternity)
    • Clinical laboratory test interpretation and reporting (e.g., genetics/genomics, oncology, histocompatibility, infectious disease, or molecular identity testing)
Application Fee (non-refundable): $250

Apply for MB(ASCP)

Beginning January 1, 2026, application fees for all ASCP certification examinations will increase by $10.

Application Fee (non-refundable): $250

Apply for MB(ASCPi)

Reduced pricing is available for those educated and residing in low-to-middle income countries

Beginning January 1, 2026, application fees for all ASCPi certification examinations will increase by $10, except for those educated and residing in low-to-middle income countries.

Information About Required Documentation

You must upload the appropriate documentation form when you apply online, verifying that you meet the training and/or experience requirements for your category and route of application. You will also need to submit an acceptable transcript or transcript evaluation verifying that you meet the academic requirements. Gather your documents before submitting your application and application fee.

Apply

Once you have confirmed that you meet the requirements and have gathered your documents, submit your online application.

Coming Soon! Digital Badges

In early 2026, the ASCP BOC will launch digital badging through Credly, a trusted provider that increases the visibility of ASCP BOC credential holders by securely showcasing and sharing professional credentials. Learn more about digital badges.

“An ASCP BOC credential adds significant value by enhancing professional credibility and demonstrating a commitment to excellence in laboratory practices. For me, it not only signifies personal growth and a mastery of essential skills but also positions me for career advancement and new opportunities. For laboratory professionals, this credential fosters a culture of continuous learning and quality improvement, which ultimately leads to better patient care and safety. Patients benefit from having highly qualified professionals managing their diagnostic processes, ensuring accurate results that guide critical treatment decisions. By standing out in the field, ASCP BOC credential holders contribute to elevating the overall standard of care in healthcare, reinforcing trust in laboratory services and improving health outcomes.”

- Sana Sajid, MB(ASCPi)CM