Diplomate in Medical Laboratory Immunology - DMLI

Obtain certification and advance your career in immunology with our specialized credential.

Directs a high complexity clinical immunology laboratory or clinical laboratory performing immunology, flow cytometry, or molecular assays. Provides oversight for test selection, evaluation, development, validation, and implementation. Responsible for appropriate test interpretation and consultation with health care providers. Certified individuals may also be involved in laboratory and medical education, research and development, quality assurance, and regulatory aspects of clinical and diagnostic immunology.

Eligibility Routes

Each credential has specific eligibility requirements. It’s your responsibility to confirm that your education, training, and/or experience meet the criteria. Submit the correct documentation with your application. Once submitted, the category and route of application cannot be changed.   

Check Your Eligibility

Diplomate in Medical Laboratory Immunology - DMLI(ASCP)

An applicant must be able to verify that they meet all eligibility requirements, including education, training, and/or experience. For complete information, see the Documentation section of the website. 

Education does not need to be from the United States. Details are available by reviewing the webpage titled Acceptable Education, also available in the routes below. 

To be eligible for this examination category, an applicant must satisfy the minimum requirements (for degrees, the stated degree or higher) of at least one of the following routes:


  • ^Doctorate = PhD in immunology, biology, chemistry, immunohematology, microbiology, or equivalent OR DrPH, MD, or DO if special training and experience is approved by the Medical Laboratory Immunology Examination Committee. A foreign degree must be equivalent to a U.S. degree which will be determined by an acceptable transcript evaluation.


  • ^Doctorate = PhD in immunology, biology, chemistry, immunohematology, microbiology, or equivalent OR DrPH, MD, or DO if special training and experience is approved by the Medical Laboratory Immunology Examination Committee. A foreign degree must be equivalent to a U.S. degree which will be determined by an acceptable transcript evaluation.

    $Acceptable Clinical Laboratory:
    CMS CLIA certificate of registration, compliance, accreditation; 
    OR DoD CLIP certificate of registration, compliance, accreditation; 
    OR JCI accreditation; 
    OR accreditation under ISO 15189;
    OR CAP; 
    OR ASHI; 
    OR other laboratory accreditation approved by the Medical Laboratory Immunology Examination Committee.

    Experience 
    To fulfill the experience requirement for Diplomate in Medical Laboratory Immunology examination, you must have laboratory experience, within the time frame required, in the following areas: 

    • Immunologic Techniques - The applicant must have experience in 3 of the 5 areas: 

      • Cell function assays 

      • Electrophoresis techniques 

      • Flow cytometry 

      • Immunoassays 

      • Molecular techniques 

    • Immunodiagnosis and Clinical Correlations - The applicant must have experience in 5 of the 7 areas: 

      • Allergic diseases 

      • Autoimmune diseases 

      • Histocompatibility/immunogenetic and transplant immunology 

      • Immunodeficiency disorders (primary and secondary) 

      • Infectious disease 

      • Inflammation 

      • Tumor immunology/hematologic disorders 

    • Clinical Laboratory Management and Operations - The applicant must have experience in ALL of these areas: 

      • Laboratory administration (e.g., financial, service operations, personnel, quality management, regulatory compliance and lab accreditation, safety programs and practices) 

      • Quality control and quality assurance 

      • Test development, validation, and implementation 

    • Doctorate^ from an accredited (regionally or nationally) college/university,   

    • AND 2 years of full-time acceptable pre-doctoral supervisory experience relevant to medical laboratory immunology in an acceptable laboratory$,  

    • AND 2 years of full-time acceptable post-doctoral training, research experience, and/or supervisory experience relevant to medical laboratory immunology in an acceptable laboratory$ within the last 5 years that must be documented on this Experience Documentation Form


    ^Doctorate = PhD in immunology, biology, chemistry, immunohematology, microbiology, or equivalent OR DrPH, MD, or DO if special training and experience is approved by the Medical Laboratory Immunology Examination Committee. A foreign degree must be equivalent to a U.S. degree which will be determined by an acceptable transcript evaluation.

    $Acceptable Clinical Laboratory:
    CMS CLIA certificate of registration, compliance, accreditation; 
    OR DoD CLIP certificate of registration, compliance, accreditation; 
    OR JCI accreditation; 
    OR accreditation under ISO 15189;
    OR CAP; 
    OR ASHI; 
    OR other laboratory accreditation approved by the Medical Laboratory Immunology Examination Committee.

    Experience 
    To fulfill the experience requirement for Diplomate in Medical Laboratory Immunology examination, you must have laboratory experience, within the time frame required, in the following areas: 

    • Immunologic Techniques - The applicant must have experience in 3 of the 5 areas: 

      • Cell function assays 

      • Electrophoresis techniques 

      • Flow cytometry 

      • Immunoassays 

      • Molecular techniques 

    • Immunodiagnosis and Clinical Correlations - The applicant must have experience in 5 of the 7 areas: 

      • Allergic diseases 

      • Autoimmune diseases 

      • Histocompatibility/immunogenetic and transplant immunology 

      • Immunodeficiency disorders (primary and secondary) 

      • Infectious disease 

      • Inflammation 

      • Tumor immunology/hematologic disorders 

    • Clinical Laboratory Management and Operations - The applicant must have experience in ALL of these areas: 

      • Laboratory administration (e.g., financial, service operations, personnel, quality management, regulatory compliance and lab accreditation, safety programs and practices) 

      • Quality control and quality assurance 

      • Test development, validation, and implementation 

Route 1 Initial Application Fee: $540 

Routes 2,3 Initial Application Fee: $575 

Examination Fee (all): $500

Note: Once submitted, fees are non-refundable



Apply for DMLI(ASCP)

Beginning January 1, 2026, application fees for all ASCP certification examinations will increase by $10.


 

Information About Required Documentation

You must upload the appropriate documentation form when you apply online, verifying that you meet the training and/or experience requirements for your category and route of application. You will also need to submit an acceptable transcript or transcript evaluation verifying that you meet the academic requirements. Gather your documents before submitting your application and application fee.

Apply

Once you have confirmed that you meet the requirements and have gathered your documents, submit your online application.

Coming Soon! Digital Badges

In early 2026, the ASCP BOC will launch digital badging through Credly, a trusted provider that increases the visibility of ASCP BOC credential holders by securely showcasing and sharing professional credentials. Learn more about digital badges.

“The ASCP BOC Diplomate in Medical Laboratory Immunology - DMLI(ASCP) certification provides validation of your competency and knowledge in immunology. It is a testimonial that you are committed to the profession, patient care, and standards of practice.”

- Anne Tebo, PhD, D(ABMLI)