Low Blood Levels Of Ceruloplasmin At Diagnosis Are Linked To Worse Survival In Adults With ANCA-Associated Vasculitis Who Test Positive For Self-Reactive Antibodies Against Myeloperoxidase Enzyme, Study Finds

ANCA Vasculitis News (10/21, Bryson) reports, “Low blood levels of the copper-carrying protein ceruloplasmin at diagnosis are associated with worse survival in adults with ANCA-associated vasculitis (AAV) who test positive for self-reactive antibodies against the myeloperoxidase...enzyme, a new study...has shown.” Investigators came to this conclusion after retrospectively analyzing “data from 92 adults with either microscopic polyangiitis...or granulomatosis with polyangiitis...the two most common types of AAV.” The findings were published in PLOS One.