Large-Language Models in the Clinical Laboratory

From Concept to Bench-Top

This immersive two-day course is designed for pathologists and laboratory professionals seeking to apply large language models (LLMs) safely and effectively in clinical, research, and operational laboratory settings. Participants will build a practical foundation in LLM fundamentals, including model families, prompt engineering strategies, regulatory and privacy guardrails, and known limitations such as hallucinations and bias—framed within the realities of regulated laboratory practice.

Key Topics

  • Core Large Language Model (LLM) concepts (models, embeddings, RAG, prompt engineering, governance).
  • Lab specific documents (policies, validation plans, letters, e mail, CV extracts) with an audit trail suitable for CLIA/CAP inspection.
  • Procedure manual lookup chatbot using Retrieval Augmented Generation.
  • LLM workflows with LIS/LIMS, scheduling, and EHR messaging.
  • Outputs for accuracy, bias, confidentiality, and regulatory compliance.

Location

ASCP Headquarters
33 W Monroe St, Chicago, IL

Date

June 15-16, 2026

Credit

12 CME/CMLE credits

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Learning Objectives

  • Explain core LLM concepts (models, embeddings, RAG, prompt engineering, governance).
  • Generate lab-specific documents (policies, validation plans, letters, e-mail, CV extracts) with an audit trail suitable for CLIA/CAP inspection.
  • Build a procedure-manual lookup chatbot using Retrieval-Augmented Generation.
  • Integrate & automate LLM workflows with LIS/LIMS, scheduling, and EHR messaging.
  • Evaluate outputs for accuracy, bias, confidentiality, and regulatory compliance.
  • Leave with actionable templates, code snippets, and a personal “starter RAG” repo.

Faculty Info

Faculty: Ul Balis, MD
Course Architect & Pedagogy Lead
Informatics Director, Educator & Data Scientist

Ron Jackups, MD, PhD
Course Co-architect
Clinical Pathologist & LIS Medical Director

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12 CME/CMLE Credits

Listed Price

$1,039.00

Membership Price

$799.00

Course Schedule

Monday, June 15, 2026

  • 8:30am – 8:45am: Welcome & Logistics
  • 8:45am – 10:15am: Plenary: “LLM Essentials for Lab Medicine”
  • 10:15am – 10:30am: Break
  • 10:30am – 12pm: Hands-on 1: Prompt Engineering for Productivity
  • 12pm – 1pm: Hosted Lunch & Vendor Fair
  • 1pm – 2:30pm: Hands-on 2: Hypothesis Generation & Literature Triaging
  • 2:30pm – 2:45pm: Break
  • 2:45pm – 4:15pm: Hands-on 3: Assay Validation Protocol Builder
  • 4:15pm – 5pm: Panel & Wrap-Up

Tuesday, June 16, 2026

  • 8:30am – 9am: Check-in
  • 9am – 10:30am: Hands-on 4: Build Your Own Procedure Manual Chatbot
  • 10:30am – 10:45am: Break
  • 10:45am – 12:15pm: Hands-on 5: Automation & Governance
  • 12:15pm – 1pm: Capstone Challenge & Debrief