Nasal Corticosteroids Linked To Increased SARS-CoV-2 Risk In Adults But Not Children, Study Finds

August 13, 2025

HCP Live (8/12, Derman) reports a study “showed that nasal corticosteroids increase the risk of SARS-CoV-2 infection in adults but not children.” In the prospective, multicenter Human Epidemiology and RespOnse to SARS-CoV-2 (HEROS) trial, researchers “aimed to assess whether nasal or inhaled corticosteroid use increased the risk of SARS-CoV-2 infection in adults and children with allergic rhinitis or asthma.” They observed that “nasal and inhaled corticosteroids were individually associated with a greater risk of SARS-CoV-2 infection among adults.” In addition, sensitivity analyses “showed the link between nasal corticosteroid use with the risk of SARS-CoV-2 infection in adults. Nasal and inhaled corticosteroid use was not linked to an increased SARS-CoV-2 risk in children.” The study (PDF) will be published in Journal of Allergy and Clinical Immunology.