Severe Manifestations Of Enterovirus D68 Uncommon In Infants, Young Children With Symptomatic, Community-Acquired Infection, Study Finds

August 07, 2025

Infectious Disease Advisor (8/6, Basilio) reports a study found that “severe manifestations of enterovirus D68 (EV-D68) in infants and young children appear to occur in only a minority of those with symptomatic, community-acquired infection.” Researchers observed that “incidence of EV-D68 infection for epidemiologic year was 0.78 per 100 child-weeks, while incidence of EV-D68 infection for the 2018 season was 1.64 per 100 child-weeks.” They noted that “from July to November 2018, at least 1 swab from 204 children was submitted, with 630 (23%) positive for rhinovirus/enterovirus. Of those, 59 (9%) were positive for EV-D68 infection.” In addition, “more than half (52%) of EV-D68 infections had a preceding viral detection within the prior 30 days.” The study was published in the Journal of the Pediatric Infectious Disease Society.