Review Finds Failure To Prevent Transmission Of HIV From Mother To Child Leads To PDR, ADR In Children

The American Journal of Managed Care (7/24, Bonavitacola) reports, “Treatment for children with HIV can be challenging, in part due to the possibility of drug resistance when attempting to target the virus.” In a review, “a failure to prevent the transmission of HIV from mother to child was found to lead to pretreatment drug resistance (PDR) and acquired drug resistance (ADR) in children.” In the review, “high prevalence of pretreatment and acquired drug resistance in children with HIV, especially in sub-Saharan Africa, was identified.” Researchers found that “nonnucleoside reverse transcriptase inhibitors are a significant source of drug resistance in pediatric HIV populations.” The findings were published in Open Forum Infectious Diseases.