Urine Biomarkers Noninvasively Assess Kidney Health In Patients With Diabetic Kidney Disease, Study Suggests

Healio (7/18, Carter) reported, “Certain urine biomarkers may noninvasively assess kidney health in patients with diabetic kidney disease and help identify risk for chronic kidney disease progression, according to study data.” Researchers found “that MCP-1 [monocyte chemoattractant protein-1], KIM-1 [kidney injury molecule-1] and EGF [epidermal growth factor] may be used to noninvasively assess tubule and interstitial health in patients with CKD and diabetes.” Investigators “found higher levels of KIM-1 and MCP-1 were associated with increased CKD progression risk, and higher urine levels of EGF were linked to lower risk of progression.” The findings were published in the Clinical Journal of the American Society of Nephrology.