Blood Test May Be Able To Predict MASLD Up To 16 Years Before It Develops, Study Suggests

MedPage Today (5/6, Haelle) reports a study presented at DDW 2025 suggests that “a new blood test can predict the development of metabolic dysfunction-associated steatotic liver disease (MASLD) up to 16 years before it occurs.” Researchers said that “an increase in the plasma concentrations of five proteins, combined with identification of clinical risk factors, could predict development of MASLD, with 90% accuracy up to 5 years early, 84% accuracy up to 10 years early, and 81% accuracy up to 16 years early.” They explained, “The five key proteins, each demonstrating high independent predictive power individually, can serve as practical biomarkers, marking a significant improvement over current models and increasing clinical applicability for routine use.”’