Study Finds Immunocompromised Patients With Asplenia/Hyposplenia Face Increased Risks From Babesiosis

April 28, 2025

Infectious Disease Advisor (4/25) reported, “The risk for complications, mortality, and disease recurrence due to babesiosis was significantly higher among patients with immunocompromising conditions” such as asplenia/hyposplenia “compared with immune-intact patients.” Between-group analyses of patients at 12 months “showed immune-intact patients had lower rates of all-cause mortality (1% vs 7%) and hospitalization (55% vs 83%), as well as shorter stays (median, 4 days vs 6 days). In contrast, disease recurrence was more common in immunocompromised patients (8% vs 0%).” The study results were published in Clinical Infectious Diseases.