Urinary DNA Methylation Test Showed Potential For Detecting High-Grade Or Invasive Bladder Cancer, Study Finds

Healio (3/25, Shinkle) reports, “A urinary DNA methylation test showed potential for detecting high-grade or invasive bladder cancer, according to results of a prospective multicenter study.” This “approach – which outperformed the nuclear matrix protein 22 (NMP22) test and urine cytology test – showed ‘excellent negative predictive value’ but its positive predictive value proved ‘suboptimal,’ researchers wrote.” The findings were published in JAMA Oncology.