Lower Blood Levels Of GPX-3 Are Associated With Greater Disease Activity, Blood Vessel Damage In People With ANCA-Associated Vasculitis, Study Finds

ANCA Vasculitis News (3/5, Lobo) reports, “Lower blood levels of glutathione peroxidase-3 (GPX-3), an antioxidant enzyme, are significantly associated with greater disease activity and blood vessel damage in people with ANCA-associated vasculitis (AAV), a study found.” Investigators wrote, “We demonstrated that [blood] GPX-3 concentration at diagnosis has the potential to be a novel biomarker that can assess and estimate activity and damage caused by AAV, although it is confined to the time of diagnosis.” The findings were published in Frontiers in Molecular Biosciences.