Polygenic Risk Score Based On Genes Associated With Endothelial Cell Function Identifies Patients At Higher Risk Of Coronary Artery Disease, Study Finds

TCTMD (2/27, O'Riordan) reports, “A polygenic risk score...based on genes associated with endothelial cell function identifies patients at a higher risk of coronary artery disease, according to a new study.” Investigators found that “the risk score, which is based on 35 single nucleotide polymorphisms...also pinpointed patients more likely to benefit from therapies that lower LDL cholesterol.” The findings were published in Nature Medicine.