Antibodies Targeting MLC1 Protein May Drive MS, Study Indicates

Multiple Sclerosis News Today (2/24) reports a study indicates that “antibodies against a protein found in neurons and in nerve supporting cells may play a role in driving multiple sclerosis (MS).” The researchers “examined immune responses against more than 23,000 human proteins, and the MLC1 protein emerged as one of the top hit proteins targeted by immune B-cells derived from” patients with MS. Although the mechanisms that “drive that inflammation in MS aren’t fully understood, B-cells appear to play a major role.” The study was published in Neurology Neuroimmunology and Neuroinflammation.