Genetic Predispositions Impacting LDL-C Levels Were Inversely Linked To Likelihood Of T2D, Analysis Finds

January 16, 2025

HCPlive (1/15, Iapoce) reports, “Genetic predispositions impacting low-density lipoprotein cholesterol (LDL-C) levels, including both monogenic and polygenic mechanisms, were inversely linked to the likelihood of type 2 diabetes (T2D), according to a new analysis.” This research, “evaluating a population of more than 361,000 adults in the United Kingdom Biobank, across a follow-up of approximately 14 years, revealed the index of T2D risk was robustly associated with the level of genetic disturbances in LDL-C levels.” The findings were published in JAMA Cardiology.