Hydrocortisone Plus Fludrocortisone Reduces Mortality Risk Among Patients With Septic Shock And Community-Acquired Pneumonia, Study Finds

Infectious Disease Advisor (4/8, Nye) reports, “Hydrocortisone plus fludrocortisone reduces the risk of mortality among patients with septic shock and community-acquired pneumonia (CAP), according to findings published in The Lancet Respiratory Medicine.” In the study, “compared with placebo recipients, patients who received hydrocortisone plus fludrocortisone exhibited a non-significantly greater number of days free from vasopressors (mean, 56 vs 45 days), ventilation (mean, 46 vs 38 days), organ failure (mean, 53 vs 42 days), ICU admission (mean, 44 days vs 35 days), and hospitalization (mean, 34 vs 27 days) at day 90.”