Increased PrEP Usage Associated With Decreased HIV Diagnosis Rates, Study Finds

July 01, 2025

American Journal of Managed Care (6/30, Bonavitacola) reports a study published in The Lancet HIV found that “higher levels of use for pre-exposure prophylaxis (PrEP) were associated with lower rates of diagnoses of HIV in the US.” According to the study, “the mean diagnosis rates of HIV declined from 13.0 to 10.6 per 100,000 between January 1, 2012, and December 31, 2022. Mean PrEP coverage increased from 0.6% to 26.3% in the same time period.” Researchers noted that “the estimated annual percentage change (EAPC) varied in HIV diagnosis rates across the country, spanning from a 6.8% decrease in Maryland to a 9.1% increase in West Virginia. The mean PrEP coverage was 10.9% in states with a decrease in EAPC of diagnosis rates of HIV and the mean PrEP coverage was 5.1% in states with significant increases in EAPC.”