Model Estimates PrEP Need Across Multiple US Subgroups, Study Finds

American Journal of Managed Care (6/24, Bonavitacola) reports a study found that a newly developed model “could estimate the need for PrEP.” The model “estimates PrEP need, aiding targeted resource allocation for vulnerable populations and supporting the US’s goal to reduce HIV infections by 90%.” The study utilizes “a 1% HIV incidence threshold to evaluate different models,” calculating the number needed to treat (NNT) for different subgroups. Researchers calculated that “1,888,130 individuals who were in subgroups of annual incidence of HIV of 1% or higher...needed to receive PrEP in 2022. Added to the number of individuals who had a prescription for PrEP in 2021, this amounts to a PPN of 2,254,489.” They concluded that “this number could act as an estimate of PrEP need in the US, which could help in targeting certain subgroups of vulnerable individuals and establish manufacturing needs across the nation.” The study was published in Annals of Epidemiology.