Invasive E Coli Disease Risk Increased Among Patients Undergoing Urologic Procedures Regardless Of Prophylactic Antibiotic Use, Study Finds

Infectious Disease Advisor (5/5, Basilio) reports a study found that “the risk for invasive Escherichia coli disease is increased among patients undergoing urologic procedures regardless of prophylactic antibiotic use.” Researchers “conducted a retrospective, claims-based cohort study from 2021 to 2023 to estimate the risk for invasive E coli disease after select elective urologic procedures with and without antibiotic prophylaxis.” They found that “patients who underwent urologic procedures without antibiotic prophylaxis showed significantly greater risk for invasive E coli disease than those who underwent procedures with prophylaxis. However, the risk was significantly lower among patients in the control cohort compared with those who underwent procedures with antibiotic prophylaxis.” Researchers concluded, “This study underscores a continued unmet need for additional preventative measures to avoid the substantial burden of IED [invasive E coli disease] after urologic procedures.” The study was published in Infectious Diseases and Therapy.