IgG Levels, Maternal And Infant Secretor Status Tied To Rotavirus Vaccine Response, Study Finds

Infectious Disease Advisor (4/11) reports, “Immunoglobulin (Ig) G levels prior to vaccination and maternal and infant secretor status are associated with rotavirus vaccine response, according to findings published in The Journal of Infectious Diseases.” According to the study, “factors significantly associated with viral shedding between 4 and 28 days following the first rotavirus vaccine dose were as follows: prevaccination IgG; time since vaccination; concordant nonsecretor status; and concordant nonsecretor vs secretor status.”