User Auth Test Page

NTCA Releases Recommendations On Pulmonary TB Public Health Practices

Infectious Disease Advisor (6/20, Mahmoud) reports, “The National Tuberculosis (TB) Coalition of America (NTCA) has released recommendations on public health practices concerning respiratory isolation and restrictions (RIR) for individuals with pulmonary TB in community settings. The recommendations were published in Clinical Infectious Diseases.” The authors wrote, “Additional research is needed to quantify the proportion of TB transmission that is avertable by community-based RIR, acknowledging that the majority of transmission may occur prior to diagnosis and any RIR interventions.”

Full Article
Artificial intelligence–based algorithms for the diagnosis of prostate cancer: A systematic review

Abstract Not Available

Full Article
Pathologist Aims to Boost Interest in Laboratory Medicine in African Country that Desperately Needs It

Abstract Not Available

Full Article
Waste Management Plus One

Abstract Not Available

Full Article
Study of the diagnostic efficiency of anti-ZnT8 autoantibodies for type 1 diabetes in pediatric patients

Abstract Not Available

Full Article
Studies Show Promise Of Sequencing Infants’ Genomes To Detect Genetic Conditions

The Washington Post (6/17, Johnson) reports that in two state studies conducted in North Carolina and New York, “parents can have experts conduct a more extensive scan and review their baby’s entire genetic blueprint for 200 different conditions” free of charge. The states “are studying whether this far more comprehensive approach can save lives and improve children’s health. Two decades after scientists sequenced the first human genome, the two state studies reflect the rapid emergence of a new kind of health care called genomic medicine, spawned by that landmark achievement.” Now, “early results show that genome sequencing is identifying conditions not disclosed through the traditional newborn screening required by all 50 states.” However, this genomic sequencing raises ethical and practical questions.

Full Article
FDA Approves Merck’s Pneumococcal Vaccine

Bloomberg Law (6/17, Garde, Subscription Publication) reports, “Merck & Co. won US approval for a pneumococcal vaccine that threatens to unseat one of Pfizer Inc.’s biggest franchises.” Merck’s shot, Capvaxive, “is approved to prevent the bacterial infections behind pneumonia and meningitis for adults over 18, Merck said Monday.” The vaccine “has the potential to become the preferred vaccine given studies have shown it protects against bacterial strains that cause around 80% of pneumococcal diseases. Pfizer’s Prevnar works against 50%, to compare.”

Full Article
Congenital Syphilis Outcomes Associated With Adverse Social Determinants Of Health, Study Finds

Infectious Disease Advisor (6/17, McSwiggin) reports, “Congenital syphilis outcomes are strongly associated with adverse social determinants of health, including inadequate prenatal care, substance use, housing instability, and interactions with the justice system.” In the study, “mothers of infants with potential congenital syphilis were predominantly Black or African American (65%) or non-Hispanic (86%), more than half (52%) indicated unemployment, and the majority (78%) resided in census tracts within the third or fourth quartiles of social vulnerability.” The findings were published in Clinical Infectious Diseases.

Full Article
Piperacillin-Tazobactam Associated With Higher Mortality Risk In Sepsis Than Cefepime, Study Finds

Infectious Disease Advisor (6/17, Nye) reports, “Compared with cefepime, piperacillin-tazobactam is associated with higher risk of mortality and increased duration of organ dysfunction among patients with suspected sepsis and no clear indication for antianaerobic antibiotic coverage, according to study results published in JAMA Internal Medicine.” In the study, “piperacillin-tazobactam vs cefepime treatment was associated with a higher 90-day mortality rate (22.5% vs 17.5%; P =.002), with an absolute increase of 5.0% (95% CI, 1.9-8.1).”

Full Article
Continuous Beta-Lactam Antibiotic Infusions More Effective At Treating Sepsis Than Intermittent Infusions, Study Finds

Healio (6/14, Hornick) reported, “More ICU patients with sepsis receiving a continuous vs. intermittent infusion of beta-lactam antibiotics achieved clinical cure by day 14, but 90-day mortality was similar, according to research published in JAMA.” In the study, “a slightly lower proportion of patients in the continuous vs. intermittent infusion group died by day 90 (24.9% vs. 26.8%), but the between group absolute difference was not statistically significant (–1.9%; 95% CI, –4.9% to 1.1%).” Nonetheless, researchers wrote “the confidence interval around the effect estimate includes a clinically important benefit.”

Full Article
Urinalysis Not Accurate For Diagnosing UTIs In Children With Spina Bifida, Study Finds

Healio (6/14, Weldon) reported, “Urinalysis did not accurately diagnose UTIs in children with spina bifida, according to study results published in Pediatrics.” In the study, “regarding the diagnostic accuracy of each UA component, pyuria had the highest sensitivity (0.91, 95% CI, 0.84-0.95) and the least specificity (0.36, 95% CI, 0.33-0.4), whereas nitrites were the least sensitive (0.52, 95% CI, 0.42-0.61) and most specific (0.72, 95% CI, 0.69-0.75).”

Full Article
Rare “Flesh-Eating Bacteria” Spreading In Japan

Bloomberg (6/15, Terukina, Subscription Publication) reported, “A disease caused by a rare ‘flesh-eating bacteria’ that can kill people within 48 hours is spreading in Japan after the country relaxed Covid-era restrictions.” Streptococcal toxic shock syndrome (STSS) cases have “reached 977 this year by June 2, higher than the record 941 cases reported for all of last year, according to the National Institute of Infectious Diseases, which has been tracking incidences of the disease since 1999.”

Full Article
Number Of CDC-Defined Influenza Risk Factors May Inform Risk For Severe Outcomes In Adults, Study Finds

Infectious Disease Advisor (6/14, McSwiggin) reported, “The number of influenza risk factors may indicate risk for severe outcomes in adult patients, according to study results published in Open Forum Infectious Diseases.” In the study, “higher cumulative number of CDC-defined risk factors was associated with increased risk for influenza-related medical encounters. The relationship between higher number of risk factors and increased risk for influenza-related ED or hospital admission was most pronounced among patients aged 50 to 64 years,” but “overall, the number of CDC-defined risk factors contributed more significantly to the risk for influenza-related medical encounters than patient age.”

Full Article
BARDA Awards $500M In Project NextGen Funding For Novel Nasal Spray Or Oral Pill COVID-19 Vaccines

Healthcare Finance News (6/14, Lagasse) reported, “The Biomedical Advanced Research and Development Authority (BARDA) is setting aside up to $500 million in Project NextGen funding to plan and execute multiple Phase 2b clinical trials evaluating novel vaccines administered as a nasal spray or as a pill to protect against symptomatic COVID-19.” As much as “$453 million will go to Vaxart of San Francisco, California, for developing an oral pill vaccine candidate.” Additionally, around “$34 million will go to Castlevax, part of the Mount Sinai Health System in New York City, developing an intranasal vaccine candidate, CVAX-01. And roughly $40 million is set to be awarded to Cyanvac of Athens, Georgia, developing an intranasal vaccine candidate, CVXGA.”

Full Article
US Officials Warn Further Spread Of Avian Flu In Dairy Cattle Presents Opportunities For Human Infections

Reuters (6/13, Douglas, Steenhuysen) reports, “Further spread of bird flu among U.S. dairy herds presents additional opportunities for human infections, federal officials said on Thursday while urging farms to take enhanced biosecurity measures to contain the virus.” H5N1 avian flu “has been reported in 94 dairy herds across 12 states since late March, according to the U.S. Department of Agriculture.” Although “the risk to public health is currently low...additional spread of the virus could increase that risk, said Nirav Shah, principal deputy director for the U.S. Centers for Disease Control and Prevention, on a briefing call with reporters.” So far, “three dairy farm workers have tested positive since the virus began circulating among dairy cows.”

Full Article
COVID-19 Infections May Offer Some Protection Against Colds Caused By Coronavirus, Study Suggests

The AP (6/12, Ungar) reported on a study that “suggests previous COVID-19 infections lower the risk of getting colds caused by milder coronavirus cousins.” The study included “COVID-19 PCR tests from more than 4,900 people who sought medical care between November 2020 and October 2021” and “found people previously infected with COVID-19 had about a 50% lower chance of having a symptomatic coronavirus-caused common cold compared with people” who were “fully vaccinated and hadn’t yet gotten COVID-19.” The AP added, “coronaviruses are thought to be responsible for about 1 in 5 colds.” The study was published in Science Translational Medicine.

Full Article
COVID-19 Mitigation Measures Disrupted RSV Seasons, Leading To More Hospitalizations In 2021 And 2022 Among Young Children, Study Finds

Healio (6/13, Weldon) reports, “COVID-19 mitigation measures disrupted the circulation of respiratory syncytial virus, leading to atypical season in 2021 and 2022 that saw higher rates of hospitalization among young children, according to research published in Pediatrics.” Researchers found that “in the five seasons from 2016 through 2020, there were a total of 4,243 hospitalizations for RSV among young children at the seven hospitals compared with 1,278 and 1,485 alone in the atypical seasons in 2021 and 2022.”

Full Article
FDA Advises Drugmakers To Target KP.2 Strain With Updated COVID-19 Vaccines

NBC News (6/13, Lovelace) reports the FDA “said Thursday it had advised drugmakers to update the Covid vaccines to target the KP.2 strain, a descendant of the highly contagious JN.1 variant that began circulating widely in the U.S. this winter.” The decision “came just over a week after an FDA advisory panel voted unanimously to recommend that the Covid vaccines for the fall be updated to target the JN.1 variant or one of its descendants.” However, after that “vote, there was a disagreement between panel members and Dr. Peter Marks, the agency’s top vaccine regulator, about which strain the agency should choose. Most panel members expressed a preference for JN.1, while Marks preferred selecting a newer strain, such as KP.2.”

Full Article
Gavi Says Frontline Health Workers In High-Risk Countries Can Use Global Ebola Vaccine Stockpile Routinely, Rather Than Just In Emergencies

Reuters (6/13, Rigby) reports, “A global stockpile of Ebola vaccines can be used to protect frontline health workers in high-risk countries routinely, rather than just as an emergency measure during outbreaks, international vaccine group Gavi said on Thursday.” The stockpile contains half a million doses, and “was established by Gavi and other global health partners in 2019 for use in outbreaks of hemorrhagic fever, which has an average fatality rate of roughly 60%.” Nearly “208,000 doses of the stockpiled Ervebo vaccine, made by Merck, were set to expire this year if unused, although some countries have already had doses shipped to them for preventative campaigns, including Democratic Republic of Congo and Uganda.” About 120,000 of these doses remain.

Full Article
Artificial intelligence–based algorithms for the diagnosis of prostate cancer: A systematic review

Abstract Not Available

Full Article

Request a Call from Customer Relations

Name *
Topic *
Phone Number *
Scheduled Date *
Scheduled Time *
Customer Id

First Name *
Last Name *
Email *
Customer ID

NTCA Releases Recommendations On Pulmonary TB Public Health Practices

Artificial intelligence–based algorithms for the diagnosis of prostate cancer: A systematic review

Pathologist Aims to Boost Interest in Laboratory Medicine in African Country that Desperately Needs It

Waste Management Plus One

Study of the diagnostic efficiency of anti-ZnT8 autoantibodies for type 1 diabetes in pediatric patients

Studies Show Promise Of Sequencing Infants’ Genomes To Detect Genetic Conditions

FDA Approves Merck’s Pneumococcal Vaccine

Congenital Syphilis Outcomes Associated With Adverse Social Determinants Of Health, Study Finds

Piperacillin-Tazobactam Associated With Higher Mortality Risk In Sepsis Than Cefepime, Study Finds

Continuous Beta-Lactam Antibiotic Infusions More Effective At Treating Sepsis Than Intermittent Infusions, Study Finds

Urinalysis Not Accurate For Diagnosing UTIs In Children With Spina Bifida, Study Finds

Rare “Flesh-Eating Bacteria” Spreading In Japan

Number Of CDC-Defined Influenza Risk Factors May Inform Risk For Severe Outcomes In Adults, Study Finds

BARDA Awards $500M In Project NextGen Funding For Novel Nasal Spray Or Oral Pill COVID-19 Vaccines

US Officials Warn Further Spread Of Avian Flu In Dairy Cattle Presents Opportunities For Human Infections

COVID-19 Infections May Offer Some Protection Against Colds Caused By Coronavirus, Study Suggests

COVID-19 Mitigation Measures Disrupted RSV Seasons, Leading To More Hospitalizations In 2021 And 2022 Among Young Children, Study Finds

FDA Advises Drugmakers To Target KP.2 Strain With Updated COVID-19 Vaccines

Gavi Says Frontline Health Workers In High-Risk Countries Can Use Global Ebola Vaccine Stockpile Routinely, Rather Than Just In Emergencies

Artificial intelligence–based algorithms for the diagnosis of prostate cancer: A systematic review