User Auth Test Page

Dried Blood Spot Biomarkers May Help Identify Congenital Heart Disease In Newborns, Study Finds

Healio (7/1, Weldon) reports, “Biomarkers in dried blood spot testing may help identify congenital heart disease in newborns, according to a study in JAMA Network Open.” In the study, researchers “found that, combined, NT-proBNP and IL-1 RL1 had a positive predictive value of identifying high-risk congenital heart disease of 95.7%, a negative predictive value of 88.1%, a sensitivity of 93.6%, and a specificity of 91.8%, with an overall accuracy of 93%.”

Full Article
Men With mHSPC And Germline Mutations At Higher Risk Of Death Than Those Without Mutations, Study Finds

Renal & Urology News (7/1, Charnow) reports, “Men with metastatic hormone-sensitive prostate cancer (mHSPC) who carry germline mutations are at higher risk for death compared with noncarriers, according to investigators.” Additionally, “carriers of BRCA2 germline mutations are at significantly elevated risk for both progression to castration-resistant prostate cancer (CRPC) and death.” These findings were published in Urologic Oncology: Seminars and Original Investigations.

Full Article
Advocates Urge Mpox Vaccination As Cases Rise

CBS News (7/1, Gounder, Moniuszko) reports, “More than two years since the initial mpox outbreak, cases are trending up again – and the word still hasn’t gotten out to everyone at risk. During Pride Month, public health officials came armed with a serious message: Get vaccinated.” Currently, “only 23% of those at risk nationwide are vaccinated.” Those at highest risk include “men who have sex with men and trans women.”

Full Article
High Bacteria Levels In Water Lead To Beach Closures Across US

ABC News (7/1, Kekatos) reports, “Beaches in several states across the country have been closed to swimmers over the last few days due to harmful levels of bacteria in the water.” Closures around the country have been tied to gram-positive Enterococcus faecalis, cyanobacteria, and E. Coli in water. In general, “the CDC recommends staying out of bodies of water – including oceans, lakes and rivers – if the water looks cloudier than usual, is discolored, or smells bad. Swimmers are also cautioned to stay out of the water if they see pipes draining into or around the water, [or] if they themselves have diarrhea.”

Full Article
Single Dose Of RSV Vaccine Effective For Three Seasons Among Older Adults, Study Finds

Infectious Disease Advisor (6/28, Nye) reported, “A single dose of the Ad26. RSV.preF–RSV prefusion (pre-F) protein vaccine was found to sustain high protective efficacy across 3 respiratory syncytial virus (RSV) seasons among older adults, according to study results published in The Lancet Infectious Diseases.” In the study, “over seasons 2 and 3 combined, RSV-associated LRTI was observed in 4 (0.2%) vaccine recipients and 17 (0.8%) placebo recipients, translating to a vaccine efficacy of 71.6% (95% CI, 26.9-94.2). Across all 3 seasons, RSV-associated LRTI was observed in 10 (0.4%) vaccine recipients and 47 (1.7%) placebo recipients, translating to a vaccine efficacy of 78.7% (95% CI, 57.3-90.4).”

Full Article
Nerve Cells In Spinal Cord Responsible For Inhibiting Motor Neurons Are Lost In Early Stages Of ALS, Study Finds

ALS News Today (6/28, Wexler) reported, “In amyotrophic lateral sclerosis (ALS), nerve cells in the spinal cord responsible for inhibiting motor neurons are lost in the early stages of the disease, before the motor neurons themselves, according to a new study done in a genetic mouse model of ALS.” In the study, published in Science Advances, “researchers also found that excitatory motor neurons are lost in later disease stages and are linked to a faster progression of neurodegeneration.”

Full Article
Study Provides Reassurance That Pasteurization Kills Bird Flu Virus In Cow’s Milk, Officials Say

The AP (6/28, Stobbe) reported, “A new study that recreated commercial pasteurization in a government lab provides reassurance that heat treatment kills bird flu virus in cow’s milk, U.S. officials said Friday.” This “study was done at a federal research center in Athens, Georgia, using custom equipment that tried to more completely recreate commercial pasteurization,” and “allowed sampling at different stages in the process.”

Full Article
Climate Change Leading To Surge In Dengue Fever Cases, Scientists Say

The Washington Post (6/30, A1, Sun, Kaplan) reports that “a record 10 million people...have fallen ill with dengue so far this year – an unprecedented surge that scientists say is fueled in part by climate change.” Increases in “global temperatures have accelerated the life cycles and expanded the ranges of the mosquitoes that carry dengue, helping spread the virus to roughly one in every 800 people on the planet in the past six months alone.” As a result, “public health officials are bracing for the virus to crop up in more temperate regions, including the southernmost portions of the United States.”

Full Article
Patients Hospitalized With COVID-19 Infection With Abnormal Biomarkers Have Worse Outcomes, Study Finds

Infectious Disease Advisor (6/28, Chan) reported, “Patients hospitalized with COVID-19 infection with less favorable 5-day virologic and immunologic biomarker trajectories have worse prognoses, according to study results published in The Lancet Microbe.” In the study, “less favorable trajectories of low anti-nucleocapsid antibody levels, high plasma nucleocapsid antigen levels, and high inflammatory biomarkers were observed over the first 5 days of COVID-19 infection for patients with high-risk clinical characteristics at baseline.”

Full Article
CDC Recommends All Americans Receive New COVID-19 Vaccines This Fall

The New York Times (6/27, Mandavilli) reports, “All Americans ages 6 months and older should receive one of the new Covid-19 vaccines when they become available this fall, scientific advisers to the Centers for Disease Control and Prevention said on Thursday.” Many “Americans have acquired layers of immunity against the coronavirus from repeat infections or vaccine doses, or both. The vaccines now offer an incremental boost, remaining effective for only a few months as immunity wanes and the virus continues to evolve.” But “across every age group, a vast majority of Americans who were hospitalized for Covid did not receive one of the shots offered last fall, according to data presented at a meeting of the C.D.C.’s Advisory Committee on Immunization Practices.”

Full Article
Pathologic Re-Review Of TURBT Specimens By GU Pathologist Changes NMIBC Risk Stratification For More Than 20% Of Patients, Study Finds

Renal & Urology News (6/27, Charnow) reports, “Pathologic re-review of transurethral resection of bladder tumor (TURBT) specimens by a dedicated genitourinary (GU) pathologist led to a change in risk stratification for more than one-fifth of patients with nonmuscle-invasive bladder cancer (NMIBC), investigators reported” in Urologic Oncology: Seminars and Original Investigations. Overall, “results showed that 21% of patients with less than cT2 disease experienced a change in American Urological Association risk stratification: 13% with an increase and 8% with a decrease.”

Full Article
Study Evaluates Optimal Second-Line ART Regimens For HIV

Infectious Disease Advisor (6/27, Nye) reports, “Dolutegravir (DTG) plus ritonavir-boosted darunavir (DRV/r) and DTG with tenofovir disoproxil fumarate (TDF) plus lamivudine (3TC) or emtricitabine (FTC) are both noninferior to DRV/r plus 2 nucleoside reverse transcriptase inhibitors (NRTIs) for HIV virologic suppression in patients who experience treatment failure on non-NRTI (NNRTI)-based first-line antiretroviral therapy (ART), according to study results published in The Lancet HIV.” In the study, “at week 48, virologic suppression was observed among 75% of patients in the standard care group, 84% of those in the DRV/r plus DTG group, and 78% of those in the DTG/TDF plus 3TC or FTC group.”

Full Article
Fidaxomicin Superior To Vancomycin As First-Line Treatment For CDI, Study Finds

Infectious Disease Advisor (6/27, McSwiggin) reports, “Among patients with Clostridioides difficile infection (CDI), fidaxomicin is superior to vancomycin as first-line treatment, according to study results published in The Journal of Infectious Diseases.” In the study, “the primary composite outcome of treatment failure occurred in 8 (9.5%) fidaxomicin recipients and 111 (21.6%) vancomycin recipients.”

Full Article
The Future of Digital Pathology

Abstract Not Available

Full Article
Microbiology Case: A 36 Year Old Male with Headache and Worsening Mental Status

Abstract Not Available

Full Article
Frequency of antithyroid antibodies in patients with primary biliary cholangitis

Abstract Not Available

Full Article
Measuring the performance of an artificial intelligence–based robot that classifies blood tubes and performs quality control in terms of preanalytical errors: A preliminary study

Abstract Not Available

Full Article
CDC Narrows Recommendations For RSV Vaccination Among Older Adults

The New York Times (6/26, Mandavilli) reports, “In an unusual move, federal health officials narrowed their recommendations for who should receive the vaccine against the respiratory syncytial virus.” The CDC “advised last year that adults age 60 or older could receive a single lifetime dose of an R.S.V. vaccine, in consultation with their health care providers.” However, “on Wednesday, scientific advisers to the agency reframed that guideline. Based on recent safety and effectiveness data, they unanimously recommended that all Americans age 75 and older receive one dose of an R.S.V. vaccine.” The AP (6/26, Stobbe) reports that originally, “the vaccine advisers refrained from saying all older Americans should get the shots because of questions about possible side effects and the duration of protection.” Although “some of those questions still exist...panel members on Wednesday declined a request by vaccine manufacturers to more forcefully recommend the shots for all Americans 60 and older.” The Hill (6/26, Choi) reports, “There are currently two available RSV vaccines approved for use in the U.S. in people over 60, Abrysvo and Arexvy. The latter is also approved for adults aged 50 to 59 who are at an increased risk for severe RSV.”

Full Article
Authorities In DRC Approve Two Mpox Vaccines Amid Outbreak

Reuters (6/26, Rigby, Rolley) reports authorities in the Democratic Republic of Congo “have approved the use of two mpox vaccines to try to tackle an upsurge in cases and a dangerous new strain spreading in the country.” The country “has seen 20,000 cases and more than 1,000 deaths from mpox, mainly among children, since the start of last year.” Officials “issued an emergency use authorization for both Bavarian Nordic’s shot, Jynneos, and LC16, made by KM Biologics, according to documents and sources involved in the process.”

Full Article
Bictegravir Associated With High Levels Of Virologic Suppression For Pregnant Patients With HIV, Study Finds

Infectious Disease Advisor (6/26, McSwiggin) reports, “The use of bictegravir in pregnant women with HIV infection is associated with high levels of virologic suppression and a favorable safety profile, according to study results published in Clinical Infectious Diseases.” In the study, “among patients who received bictegravir during pregnancy, the mean gestational age at treatment initiation was 24.7 weeks, most (91.5%) achieved a virologic load of fewer than 200 copies/mL by the time of delivery, and 9 patients had detectable viremia at the time of delivery, 2 of whom had been on bictegravir for fewer than 4 weeks.”

Full Article

Request a Call from Customer Relations

Name *
Topic *
Phone Number *
Scheduled Date *
Scheduled Time *
Customer Id

First Name *
Last Name *
Email *
Customer ID

Dried Blood Spot Biomarkers May Help Identify Congenital Heart Disease In Newborns, Study Finds

Men With mHSPC And Germline Mutations At Higher Risk Of Death Than Those Without Mutations, Study Finds

Advocates Urge Mpox Vaccination As Cases Rise

High Bacteria Levels In Water Lead To Beach Closures Across US

Single Dose Of RSV Vaccine Effective For Three Seasons Among Older Adults, Study Finds

Nerve Cells In Spinal Cord Responsible For Inhibiting Motor Neurons Are Lost In Early Stages Of ALS, Study Finds

Study Provides Reassurance That Pasteurization Kills Bird Flu Virus In Cow’s Milk, Officials Say

Climate Change Leading To Surge In Dengue Fever Cases, Scientists Say

Patients Hospitalized With COVID-19 Infection With Abnormal Biomarkers Have Worse Outcomes, Study Finds

CDC Recommends All Americans Receive New COVID-19 Vaccines This Fall

Pathologic Re-Review Of TURBT Specimens By GU Pathologist Changes NMIBC Risk Stratification For More Than 20% Of Patients, Study Finds

Study Evaluates Optimal Second-Line ART Regimens For HIV

Fidaxomicin Superior To Vancomycin As First-Line Treatment For CDI, Study Finds

The Future of Digital Pathology

Microbiology Case: A 36 Year Old Male with Headache and Worsening Mental Status

Frequency of antithyroid antibodies in patients with primary biliary cholangitis

Measuring the performance of an artificial intelligence–based robot that classifies blood tubes and performs quality control in terms of preanalytical errors: A preliminary study

CDC Narrows Recommendations For RSV Vaccination Among Older Adults

Authorities In DRC Approve Two Mpox Vaccines Amid Outbreak

Bictegravir Associated With High Levels Of Virologic Suppression For Pregnant Patients With HIV, Study Finds