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HHS Ended Oversight Of Laboratory Developed Coronavirus Tests In August, STAT Investigation Reveals

A STAT (11/2, McLaughlin) investigation discovered that top HHS officials ended already-minimal oversight of laboratory developed coronavirus “tests (LDTs) in mid-August, despite being informed that the tests were plagued with quality issues.” In the summ...

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Three Studies Identify Genetic Mutations In BRCA2, PALB2, And ATM Genes Tied To Prostate Cancer Risk In Men With Strong Family History

Cancer Network (11/2, Slater) reports, “The collective findings of a series of articles published in the journals European Urology, Journal of the National Cancer Institute, and International Journal of Cancer indicate that genetic alterations in the BRCA...

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Fragment Analysis May Be Able To Detect Large MET Exon 14 Skipping Deletions In NSCLC Tumors Missed By NGS, Research Suggests

Cancer Network (11/2, Slater) reports researchers “found that a comparison of 2 techniques used in the screening of non-small cell lung cancer (NSCLC) tumor samples revealed that fragment analysis had the ability to detect large MET exon 14 skipping delet...

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Number Of New Coronavirus Cases Hit New Record High Last Week

Reuters (11/2, Shumaker) reports the number of new coronavirus cases in the US “hit another record high last week, rising 18% to more than 575,000, while deaths inched up 3%, according to a Reuters analysis of state and county reports.” Reuters adds, “The...

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In People With Mild, Asymptomatic SARS-CoV-2 Infection, Cellular Immunity To The Virus May Be Present After Six Months, Study Suggests

Reuters (11/2, Kelland) reports researchers in the UK “analysed the blood of 100 patients six months after they had had either mild or asymptomatic” SARS-CoV-2 infections and found that “cellular immunity” to the virus “is present after six months...sugge...

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CDC Study Says Pregnant Women Face Higher Risk For Developing Severe COVID-19 If Infected With SARS-CoV-2

The New York Times (11/2, Rabin) reports a CDC study indicates that pregnant woman infected with SARS-CoV-2 are at higher risk for developing severe COVID-19. The CDC “study found they were significantly more likely to require intensive care, to be connec...

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Women Diagnosed With COVID-19 While Pregnant May Be More Likely To Have Preterm Birth, CDC Report Indicates

TIME (11/2, Ducharme) reports women who are diagnosed with COVID-19 while pregnant may be at higher risk for preterm birth, according to a CDC report. The CDC report “is based on data from almost 4,500 people who were diagnosed with COVID-19 during pregna...

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Corticosteroids Plus Tocilizumab May Be Superior To Standard Of Care In Patients With COVID-19 Cytokine Storm, Study Indicates

Healio (11/2, Laday) reported researchers found “corticosteroids plus tocilizumab demonstrated superior survival outcomes compared with standard [of] care and corticosteroids alone, or alongside anakinra, in patients with COVID-19 cytokine storm.” The fin...

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Researchers Examine Rapid Coronavirus Testing Turnaround Times For Nursing Homes

Modern Healthcare (10/30, Christ, Subscription Publication) reported “researchers at the University of Rochester, Harvard and Brigham and Women’s Hospital” conducted a study examining turnaround times for rapid coronavirus tests from nursing homes and “fo...

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Coronavirus Testing Rates Reportedly Higher In New York City’s Wealthiest Neighborhoods Than Poorest Ones

The New York Times (10/30, Bellafante) reported that coronavirus testing tends to be more prevalent in the wealthiest neighborhoods of New York City and less prevalent in the poorest ones. According to the New York Times, “the wealthiest neighborhoods – i...

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FDA Approves Companion Diagnostic For Detection Of Defined Mutations Of EGFR Gene In Patients With NSCLC

Cancer Network (10/30, Slater) reported the FDA “approved expanded claims for the Cobas EGFR Mutation Test v2 as a companion diagnostic for a broader group of therapies in the treatment of non-small cell lung cancer (NSCLC), according to Roche, the develo...

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Researchers Develop Genetic Test To Help Identify Patients With Cancer At Highest Risk For Complication From Treatment With Bevacizumab

Medscape (10/30, Osterweil, Subscription Publication) reported, “Up to 40% of patients with cancer who are treated with bevacizumab develop severe hypertension and renal toxicity,” but researchers have developed a “genetic test performed before treatment”...

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US Has Had More Than Nine Million Coronavirus Cases

Reuters (10/30, Ahluwalia, B) reported there have been more than nine million cases of coronavirus in the US as of Friday. Reuters adds, “On Thursday, the United States reported a record 91,254 new cases,” and “on average, over 77,000 cases are being repo...

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SARS-CoV-2 Spike Proteins May Trigger A Proinflammatory Response In Brain Endothelial Cells That Can Affect The Blood-Brain Barrier, Study Indicates

Healio (10/30, Ernst) reported researchers found “SARS-CoV-2 spike proteins triggered a proinflammatory response in brain endothelial cells that may influence a change in the function of the blood-brain barrier.” The findings were published in Neurobiolog...

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Humoral Immune Response To SARS-CoV-2 Infection May Be Similar Among People With And Without Diabetes, Study Indicates

Medwire News (10/30, Barnard) reported researchers found “the humoral immune response to SARS-CoV-2 infection is similar in people with and without diabetes and is not influenced by hyperglycemia.” The findings were published in Diabetologia.

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Portable Ultrasound Scans May Be More Sensitive Than X-Rays For Detecting Atypical Pneumonia In Patients Who May Have COVID-19, Research Suggests

MedPage Today (11/1, Dotinga) reports researchers found “portable ultrasound scans were more sensitive than x-rays at the preliminary detection of atypical pneumonia in patients who may have COVID-19.” The findings were presented at the virtual ACEP meeti...

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Incidence Of Herpes Zoster Appears To Have Increased From 1994 To 2018, Study Indicates

Drug Topics (10/30, Longware Duff) reported researchers reviewed incidence rates of herpes zoster from 1994 to 2018 and found that the incidence “has been steadily on the rise over recent decades despite FDA approval of shingles vaccines in 2006 and 2017....

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New Cases Of Polio On The Rise Globally

NPR (10/30, Beaubien) reported that the global campaign to eradicate polio appeared in recent years to be on the verge of achieving its goal, “but now cases are on the rise and expected to climb even further in the coming months.” This year so far, “offic...

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State Health Officials Consider How To Use Rapid Coronavirus Tests Provided By Federal Government

CQ Roll Call (10/29, McIntire) reports state health officials are still deciding how to use the rapid coronavirus tests that the federal government sent to them. The Trump Administration hoped states would use the tests to help reopen schools, but some st...

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Researchers Identify Cancer Drivers In Tumors Of Almost All Patients With High-Risk Pediatric Cancer Participating In Prospective Precision Medicine Program

Cancer Therapy Advisor (10/29, Moench) reports researchers identified “one or more cancer drivers...in the tumors of almost all patients participating in a prospective, Australian-based precision medicine program focused on the extensive molecular charact...

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HHS Ended Oversight Of Laboratory Developed Coronavirus Tests In August, STAT Investigation Reveals

Three Studies Identify Genetic Mutations In BRCA2, PALB2, And ATM Genes Tied To Prostate Cancer Risk In Men With Strong Family History

Fragment Analysis May Be Able To Detect Large MET Exon 14 Skipping Deletions In NSCLC Tumors Missed By NGS, Research Suggests

Number Of New Coronavirus Cases Hit New Record High Last Week

In People With Mild, Asymptomatic SARS-CoV-2 Infection, Cellular Immunity To The Virus May Be Present After Six Months, Study Suggests

CDC Study Says Pregnant Women Face Higher Risk For Developing Severe COVID-19 If Infected With SARS-CoV-2

Women Diagnosed With COVID-19 While Pregnant May Be More Likely To Have Preterm Birth, CDC Report Indicates

Corticosteroids Plus Tocilizumab May Be Superior To Standard Of Care In Patients With COVID-19 Cytokine Storm, Study Indicates

Researchers Examine Rapid Coronavirus Testing Turnaround Times For Nursing Homes

Coronavirus Testing Rates Reportedly Higher In New York City’s Wealthiest Neighborhoods Than Poorest Ones

FDA Approves Companion Diagnostic For Detection Of Defined Mutations Of EGFR Gene In Patients With NSCLC

Researchers Develop Genetic Test To Help Identify Patients With Cancer At Highest Risk For Complication From Treatment With Bevacizumab

US Has Had More Than Nine Million Coronavirus Cases

SARS-CoV-2 Spike Proteins May Trigger A Proinflammatory Response In Brain Endothelial Cells That Can Affect The Blood-Brain Barrier, Study Indicates

Humoral Immune Response To SARS-CoV-2 Infection May Be Similar Among People With And Without Diabetes, Study Indicates

Portable Ultrasound Scans May Be More Sensitive Than X-Rays For Detecting Atypical Pneumonia In Patients Who May Have COVID-19, Research Suggests

Incidence Of Herpes Zoster Appears To Have Increased From 1994 To 2018, Study Indicates

New Cases Of Polio On The Rise Globally

State Health Officials Consider How To Use Rapid Coronavirus Tests Provided By Federal Government

Researchers Identify Cancer Drivers In Tumors Of Almost All Patients With High-Risk Pediatric Cancer Participating In Prospective Precision Medicine Program