New Duffy Null Phenotype ICD-10 Codes Adopted

ASCP worked with the American Society of Hematology (ASH), to enact new ICD-10-CM codes to describe Duffy phenotype. These codes were included in the recently released FY25 Medicare Inpatient Prospective Payment System (IPPS) Proposed Rule. Creation of the new ICD-10-CM codes represents a major policy win and an important step toward more equitable care in the laboratory and beyond. ASH requested the codes through the public code process last year, and ASCP lent our support to this effort. ASH member, Maureen Achebe, MD, MPH, participated in a public meeting to advocate, on behalf of ASH, for inclusion of Duffy phenotype codes in the ICD-10-CM code listing. The codes will be available for use beginning October 1, 2024.

CMS lists new ICD-10-CM codes in tables released with the IPPS proposed rule. The new codes are:

• Z67.A1: Duffy Null
• Z76.A2: Duffy a positive
• Z76.A3: Duffy b positive
• Z76.A4: Duffy a and b positive

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