Cell-Free DNA Analyses Were Accurate In Detecting Fetal Antigen Status As Early As 10 Weeks’ Gestation In Women With Alloimmunized Pregnancies, Study Finds

Healio (8/19, Welsh) reports, “Cell-free DNA analyses were accurate in detecting fetal antigen status as early as 10 weeks’ gestation in women with alloimmunized pregnancies, according to results of a large, diverse U.S. cohort study.” Overall, investigators “observed 100% consistency between cell-free DNA analyses and neonatal genotype for 465 antigen calls,” which included “190 antigen calls wherein the mother was alloimmunized and 275 wherein the mother was not alloimmunized but was genotype negative and able to become alloimmunized.” The findings were published in Obstetrics & Gynecology.