Racial Discrimination In Midlife May Contribute To Greater Alzheimer Disease Pathology And Neurodegeneration In Later Life Among Black Americans, Study Finds

Neurology Advisor (5/28, Nye) reports, “Racial discrimination in midlife could contribute to greater Alzheimer disease (AD) pathology and neurodegeneration in later life among Black Americans, according to study results.” Investigators “conducted a systematic review to assess the extent to which exposure to racial discrimination during middle age predicts increases in the biomarkers of AD and neurodegeneration later in life.” The researchers found that “the experience of discrimination in midlife was related with changes in serum phosphorylated tau181 (p-tau181), neurofilament light (NfL), and glial fibrillary acid protein (GFAP) between 2008 and 2019.” The findings were published in Alzheimer’s & Dementia.