CDC’s Framework To Prevent Hospital-Onset C. Diff Infections Not Linked To Reduced Incidence, Study Finds

Infectious Disease Advisor (5/23, Nye) reports, “Implementation of the United States Centers for Disease Control and Prevention’s (CDC) Strategies to Prevent Clostridioides difficile Infection in Acute Care Facilities Framework is not temporally associated with reduced incidence of hospital-onset C difficile infection (CDI), according to study results published in JAMA Network Open.” In the study, “a significant decline in annual hospital-onset CDI incidence was observed in the pre-intervention period (IRR, 0.76; 95% CI, 0.68-0.85; P <.01), but the rate of decline did not significantly differ in the post-intervention period (IRR, 0.98; 95% CI, 0.77-1.24; P =.85).”