Shorter Courses Of Antibiotics Associated With Increased Risk Of Reinfection, Mortality Among Infants In NICU With E. Coli Bacteremia, Study Finds

Healio (5/4, Weldon) reported, “Shorter courses of antibiotics were associated with increased odds of reinfection and death among infants treated in the NICU for Escherichia coli bacteremia who were not evaluated for meningitis, a study showed.” In the study, “infants who received 14 to 21 days of antibiotics or more than 21 days were far less likely to experience the combined outcome of recurrence of infection or death, with ORs of 0.14 (95% CI, 0.09-0.22) and 0.2 (95% CI, 0.13-0.31), respectively, compared with infants who received less than 14 days of therapy.” The results were presented at the Pediatric Academic Societies Meeting.