Switching To Oral Antibiotics Noninferior To IV Antibiotics For Low-Risk S. Aureus Bloodstream Infection, Study Finds

MedPage Today (1/19, Kahn) reported, “An early switch to oral antibiotics in patients hospitalized with low-risk Staphylococcus aureus bloodstream infection was noninferior to IV antibiotics, according to the randomized controlled SABATO trial.” According to the study, which was published in Lancet Infectious Diseases, “the 0.7% (95% CI -7.8 to 9.1) treatment difference between the two groups met the noninferiority margin of less than 10% (P=0.013). Hospital stays were also shorter in patients switched to oral treatment (median 12 vs 16 days, respectively).”