Oral Simnotrelvir/Ritonavir Treatment Shortens COVID-19 Illness, Lowers Viral Loads, Trial Finds

MedPage Today (1/17, Kahn) reports that “with oral simnotrelvir/ritonavir treatment in a vaccinated population, COVID-19 symptoms went away about 1.5 days earlier and SARS-CoV-2 viral loads fell, a” trial found. The research found that “in patients with mild-to-moderate COVID-19, the median time to sustained symptom resolution was significantly shortened from 216 hours to approximately 180 hours when simnotrelvir/ritonavir was taken within 72 hours of symptom onset and continued twice daily for 5 days.” The findings were published in the New England Journal of Medicine.