Heavy Binge Drinking, High Polygenic Risk Score Linked To Sixfold Higher Risk For Alcohol-Related Cirrhosis, Research Suggests

Healio (12/14, Burba) reports, “Heavy binge drinking and high polygenic risk score [PRS] were associated with a sixfold higher relative excess risk for alcohol-related cirrhosis [ARC], with the presence of diabetes mellitus further increasing the risk, researchers reported.” The analysis “demonstrated that as PRS increased within each alcohol consumption group, there was higher risk for ARC, with the ‘most marked’ effect among those in the heavy binge drinking group.” The findings were published in Nature Communications.