Fecal Metabolite Profiling May Help Predict Postoperative Infections In Patients Who Received Liver Transplants, Study Finds

HCP Live (12/29, Brooks) reported, “Fecal metabolite profiling may be a viable tool for predicting postoperative infections in patients who received liver transplants, according to findings from a” study. In the study, “fecal metabolites were quantified for more than 100 patients undergoing liver transplantation and correlated with fecal microbiome compositions, pathobiont expansion, and postoperative infections, demonstrating reduced fecal concentrations of short- and branched-chain fatty acids, secondary bile acids, and tryptophan metabolites were associated with compositional microbiome dysbiosis and the relative risk of postoperative infection.” The findings were published in Cell Host & Microbe.