Benefits Of Suppressive Antibiotic Therapy For Patients With Periprosthetic Joint Infections May Be Limited, Study Finds

Healio (5/7, Stulpin) reports, “Despite suppressive antibiotic therapy being a routine strategy for managing periprosthetic joint infections [PJIs], a study showed the benefits may be limited.” For the study, published in Open Forum Infectious Diseases, researchers looked at 167 patients with PJIs who received suppressive antibiotic therapy (SAT) “and 343 who did not – with 66 treatment failures reported. Overall, the researchers found no significant association between SAT and treatment failure (HR = 1.37; 95% CI, 0.79-2.39), although they noted that treatment failure occurred in 39 patients on SAT and 27 not on SAT.”