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Study Suggests HPV Awareness Campaigns Should Consider Education Levels, Race/Ethnicity

Infectious Disease Advisor (1/11, Barowski, RN) reports that results of a study “suggest the need to consider education level and race/ethnicity in the design of human papillomavirus awareness campaigns.” The findings were published in JAMA Network Open.

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Lack Of Reliable Transportation Could Have Negative Impacts On Health, CDC Analysis Finds

The Hill (1/11, Nazzaro) reports, “A lack of reliable transportation could have adverse health outcomes, especially among adults who are older, uninsured and have lower incomes,” according to the CDC. According to the analysis, “about 5.7 percent of adults – between 13 million and 14 million people – lacked reliable transportation for daily living in 2022.” Notably, “the percentage of those lacking reliable transportation decreases with age,” while “as family income and education level increased, the number of those without reliable transportation decreased.”

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Genetic Risk For MS Was Brought Into Europe By Sheep And Cattle Herders Migrating From The East Approximately 5,000 Years Ago, Research Suggests

MedPage Today (1/10, George) reports, “Genetic risk for multiple sclerosis (MS) was brought into Europe by sheep and cattle herders migrating from the east approximately 5,000 years ago, DNA profiles from archaeological bones and teeth suggested.” Investigators found tat “migration among pastoralists from the Pontic steppe – a region that includes parts of what are now Ukraine, Russia, and Kazakhstan – brought genetic variants that, in a modern environment, raise the risk of MS.” But, “in the past...these variants may have served a purpose: they likely protected livestock herders against pathogens from their domesticated animals.” The findings were published in Nature.

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Recurrent UTIs Caused By Cephalosporin-Resistant Enterobacterales Are Common Among Patients With Neurogenic Bladder, History Of UTIs, And Fluoroquinolone Nonsusceptibility, Study Finds

Infectious Disease Advisor (1/10, Wei) reports, “Recurrent community-onset urinary tract infections caused by extended-spectrum cephalosporin-resistant Enterobacterales are common among patients with neurogenic bladder, a history of UTIs, and fluoroquinolone nonsusceptibility, according to” a study. The findings were published in Open Forum Infectious Diseases.

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Patients With COVID-19 Infection Who Received Nirmatrelvir-Ritonavir More Likely To Experience Viral Rebound, Study Indicates

Infectious Disease Advisor (1/10, Barowski, RN) reports, “Although nirmatrelvir-ritonavir is associated with fewer COVID-19 symptoms and reduced viral load, it may increase risk for viral rebound,” according to a study. The findings were published in Clinical Infectious Diseases.

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Holiday Gatherings Increased COVID-19 Transmission Globally, WHO Director Says

The AP (1/10) reports, “The head of the U.N. health agency said Wednesday holiday gatherings and the spread of the most prominent variant globally led to increased transmission of COVID-19 last month.” WHO Director-General Tedros Adhanom Ghebreyesus “said nearly 10,000 deaths were reported in December, while hospital admissions during the month jumped 42% in nearly 50 countries – mostly in Europe and the Americas – that shared such trend information.”

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FDA Allows Temporary Importation Of Syphilis Drug To Address Shortages

Reuters (1/10, Santhosh) reports the FDA “will temporarily allow the import of a syphilis drug made by France’s Laboratoires Delbert, the company said on Wednesday.” According to a letter on the FDA’s website, “Laboratoires Delbert said it was coordinating with the health regulator to bring extencilline into the United States to address syphilis drug shortages.” The Hill (1/10, Weixel) reports, “Benzathine penicillin G is the preferred treatment for syphilis, and the only recommended treatment for pregnant people and infants with possible syphilis,” although “it’s been in shortage since April.” Meanwhile, “Pfizer, which is the only company manufacturing the drug in the U.S., said it would take until at least the second quarter of 2024 to increase production enough to end the shortage.”

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Staying In A Hospital Room Or Bed Previously Occupied By Someone With C. Difficile Nearly Doubles Risk For Infection, Study Finds

Healio (1/9, Stulpin) reports, “Staying in a hospital room or bed previously occupied by someone with Clostridioides difficile nearly doubles a patient’s risk for hospital onset-C. difficile infection, researchers found.” The findings were published in Infection Control & Hospital Epidemiology.

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Measles Outbreak In Philadelphia Widens To Eight Known Cases

CNN (1/9, Hassan) reports, “A cluster of measles cases in Philadelphia has widened to include eight people over the past month, including at least five children, according to the city’s health department.” Notably, “a person who contracted measles outside the United States went to Children’s Hospital of Philadelphia in early December, the health department said, exposing three people at the hospital who later tested positive for the highly contagious virus.” Further exposures were detected at a Philadelphia day care attended by one of the patients.

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Study Finds Influenza Vaccination Significantly Decreased Risk For Pediatric Hospitalizations, ED Admissions, And Urgent Care Visits

Infectious Disease Advisor (1/9, Barowski) reports, “Influenza vaccination was found to significantly decrease the risk for influenza A-associated hospitalizations, emergency department admissions, and urgent care visits among children and adolescents during the 2022 to 2023 influenza season,” according to a study. The findings were published in Clinical Infectious Diseases.

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Healthcare Providers Who Commonly Care For Patients With STIs More Likely To Prescribe Prophylactic Doxycycline, Survey Indicates

Infectious Disease Advisor (1/9, Chan) reports, “Health care providers who commonly care for patients with sexually transmitted infections are more likely to prescribe prophylactic doxycycline and believe that the benefits of its use outweigh the risk for antimicrobial resistance, according to survey results.” The findings were published in Emerging Infectious Diseases.

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Higher Out-Of-Pocket Costs For HIV Pre-Exposure Prophylaxis Projected To Lead To More People Discontinuing PrEP Altogether, Analysis Finds

MedPage Today (1/8, Kahn) reports, “Higher out-of-pocket costs for HIV pre-exposure prophylaxis were projected to lead to more people discontinuing PrEP altogether in a new analysis, raising concerns about a possible rise in HIV infections.” Notably, “even a small increase in out-of-pocket cost – from $0 to $10 per monthly PrEP prescription – was projected to double the rate of PrEP abandonment from 5.6% to 11.1%...reported” researchers. The results were published in Health Affairs.

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Single Dose Of AS01E-Adjuvanted RSV Prefusion F Protein-Based Vaccine Elicits RSV-A And RSV-B-Specific Immune Responses Among Older Adults, Study Finds

Infectious Disease Advisor (1/8, Nye) reports, “A single dose of the AS01E-adjuvanted respiratory syncytial virus prefusion F protein-based vaccine elicits RSV-A and RSV-B-specific immune responses among older adults.” The findings were published in The Journal of Infectious Diseases.

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Inflammatory Biomarker Levels Among Patients With HIV Infection Similar Between Those Who Switch To DTG/3TC And Those Who Remain On TAF-Based Antiretroviral Regimens, Study Finds

Infectious Disease Advisor (1/8, Nye) reports, “Results of a study ... suggest that inflammatory biomarker levels among patients with HIV infection are similar between those who switch to dolutegravir plus lamivudine and those who remain on tenofovir alafenamide-based antiretroviral regimens.” The findings were published in Open Forum Infectious Diseases.

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Two Doses Of Recombinant Zoster Vaccine Provide Strong Protection Against Shingles, Study Indicates

Healio (1/8, Rhoades) reports, “Two doses of the recombinant zoster vaccine provided strong protection over 4 years, even in patients taking corticosteroids who are at higher risk for herpes zoster, also known as shingles, according to researchers.” The findings were published in Annals of Internal Medicine.

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Flu And COVID-19 Infections Surge As Holiday Season Ends, CDC Says

The AP (1/5, Stobbe) reported, “The flu season in the U.S. is getting worse but it’s too soon to tell how much holiday gatherings contributed to a likely spike in illnesses.” CDC data posted last week “show 38 states with high or very high levels for respiratory illnesses with fever, cough and other symptoms,” up from 31 states the week prior. While the data also reflects people with COVID-19, RSV and other winter viruses, “flu seems to be increasing most dramatically,” according to the CDC. NBC News (1/6, Syal) and The Hill (1/7, Choi) also covered the story.

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Smaller Doses Of 2-Dose Mpox Vaccine Produce Detectable Immune Responses In Patients With And Without HIV Infection Regardless Of Vaccination Route, Study Finds

Infectious Disease Advisor (1/5, Nye) reported, “Smaller doses of the 2-dose mpox vaccine produce detectable immune responses in patients with and without HIV infection regardless of vaccination route.” The findings were published in The New England Journal of Medicine.

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CDC Projects JN.1 Variant Accounts For Nearly 62% Of COVID-19 Cases In US

Reuters (1/5, Roy) reported the CDC “said on Friday that COVID subvariant JN.1 accounts for about 62% of cases in the U.S. as of Jan. 5, according to the agency’s projections.” According the agency, JN.1 “is now the most widely circulated variant in the U.S.,” and “is also the dominant variant in Europe and is rising sharply in Asia.”

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FDA Allows Florida To Import Prescription Drugs From Canada

The New York Times (1/5, A1, Jewett, Stolberg, Longman) reported the FDA “has allowed Florida to import millions of dollars worth of medications from Canada at far lower prices than in the United States, overriding fierce decades-long objections from the pharmaceutical industry.” Notably, “Florida has estimated that it could save up to $150 million in its first year of the program, importing medicines that treat H.I.V., AIDS, diabetes, hepatitis C and psychiatric conditions.” Other states have applied to the FDA seeking to set up similar programs.

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Interventions Based On A Systemic Approach Can Improve Appropriate Antibiotic Prescribing Among Clinicians, Study Indicates

Infectious Disease Advisor (1/5, Wei) reported, “To improve appropriate antibiotic prescribing among clinicians, study findings ... suggest that interventions based on a systemic approach rather than individual variables alone are needed.” The findings were published in the Journal of Hospital Infection.

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Study Suggests HPV Awareness Campaigns Should Consider Education Levels, Race/Ethnicity

Lack Of Reliable Transportation Could Have Negative Impacts On Health, CDC Analysis Finds

Genetic Risk For MS Was Brought Into Europe By Sheep And Cattle Herders Migrating From The East Approximately 5,000 Years Ago, Research Suggests

Recurrent UTIs Caused By Cephalosporin-Resistant Enterobacterales Are Common Among Patients With Neurogenic Bladder, History Of UTIs, And Fluoroquinolone Nonsusceptibility, Study Finds

Patients With COVID-19 Infection Who Received Nirmatrelvir-Ritonavir More Likely To Experience Viral Rebound, Study Indicates

Holiday Gatherings Increased COVID-19 Transmission Globally, WHO Director Says

FDA Allows Temporary Importation Of Syphilis Drug To Address Shortages

Staying In A Hospital Room Or Bed Previously Occupied By Someone With C. Difficile Nearly Doubles Risk For Infection, Study Finds

Measles Outbreak In Philadelphia Widens To Eight Known Cases

Study Finds Influenza Vaccination Significantly Decreased Risk For Pediatric Hospitalizations, ED Admissions, And Urgent Care Visits

Healthcare Providers Who Commonly Care For Patients With STIs More Likely To Prescribe Prophylactic Doxycycline, Survey Indicates

Higher Out-Of-Pocket Costs For HIV Pre-Exposure Prophylaxis Projected To Lead To More People Discontinuing PrEP Altogether, Analysis Finds

Single Dose Of AS01E-Adjuvanted RSV Prefusion F Protein-Based Vaccine Elicits RSV-A And RSV-B-Specific Immune Responses Among Older Adults, Study Finds

Inflammatory Biomarker Levels Among Patients With HIV Infection Similar Between Those Who Switch To DTG/3TC And Those Who Remain On TAF-Based Antiretroviral Regimens, Study Finds

Two Doses Of Recombinant Zoster Vaccine Provide Strong Protection Against Shingles, Study Indicates

Flu And COVID-19 Infections Surge As Holiday Season Ends, CDC Says

Smaller Doses Of 2-Dose Mpox Vaccine Produce Detectable Immune Responses In Patients With And Without HIV Infection Regardless Of Vaccination Route, Study Finds

CDC Projects JN.1 Variant Accounts For Nearly 62% Of COVID-19 Cases In US

FDA Allows Florida To Import Prescription Drugs From Canada

Interventions Based On A Systemic Approach Can Improve Appropriate Antibiotic Prescribing Among Clinicians, Study Indicates