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Metabolomics: A New Tool to Reveal the Nature of Diabetic Kidney Disease

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3 Questions with Marsha Kinney, MD, MASCP

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Cases Of Omicron Subvariants BQ.1.1, BQ.1 In US Surpass BA.5, Data Show

NBC News (11/16, Bendix) reports, “Two new omicron subvariants have overtaken BA.5 as the prevailing versions of the coronavirus in the U.S.” CDC data “published Friday showed that the new subvariants – called BQ.1.1 and BQ.1 – have taken over,” and “toge...

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Seroconversion To HIV Positivity During Dapivirine Vaginal Ring Use Does Not Increase Risk For Poor Outcomes Of Subsequent ART In Women, Analysis Finds

Infectious Disease Advisor (11/16, Nye) reports, “Seroconversion to HIV positivity during dapivirine vaginal ring use does not increase the risk for poor outcomes of subsequent antiretroviral therapy (ART) in women, according to...a post hoc analysis” of...

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In Children Exposed To TB, Chest Radiography May Help In Detecting Asymptomatic Coprevalent TB, Predicting Incident TB After Baseline, Research Suggests

Healio (11/16, Hornick) reports, “In children exposed to tuberculosis, chest radiography helped in detecting asymptomatic coprevalent TB and predicting incident TB after baseline,” researchers concluded in a study that “evaluated 4,452 children from Septe...

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No Association Detected Between COVID-19 Vaccination, Herpes Zoster Infection In Study

MedPage Today (11/16, Hein) reports, “No association was detected between COVID-19 vaccination and herpes zoster infection in a database study involving more than 2 million individuals in the U.S.” Using “a self-controlled risk interval (SCRI) analysis, t...

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Drugmakers Struggle To Keep Up With Coronavirus Mutations

Bloomberg (11/16, Muller) reports, “Covid-19’s constant mutations have proven nearly impossible for drugmakers to keep up with.” The latest Omicron subvariants “threaten to render the last two antibody drugs on the market ineffective: Eli Lilly & Co.’s be...

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WHO Director-General Expects First Ebola Vaccine Doses To Arrive In Uganda Next Week

The AP (11/16, Stobbe) reports WHO Director-General Tedros Adhanom Ghebreyesus “said Wednesday that he expects the first doses of Ebola vaccine targeting the strain behind an outbreak in Uganda to arrive in the country next week.” He “said an expert commi...

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Haiti’s Cholera Situation Worsening As COVID-19 Cases Increase In The Americas, PAHO Says

Reuters (11/16, Grattan) reports “the cholera situation in Haiti continues to worsen while COVID-19 cases rose over the past week, the Pan American Health Organization (PAHO) said on Wednesday.” Health authorities in Haiti “have confirmed over 700 cases o...

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FDA Issues EUA To Roche’s Monkeypox Test

Reuters (11/15, Leo) reports that on Tuesday, the FDA issued an emergency use authorization (EUA) “to Roche’s test for the detection of DNA from monkeypox virus in swab specimens collected from people suspected of the virus infection.” Roche’s “tests will...

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Single Infusion Of CRISPR/Cas9-Based Treatment Appears Safe In Patients With Hereditary Angioedema, Interim Trial Results Suggest

MedPage Today (11/15, Boyles) reports, “The future medical promise of CRISPR/Cas9 gene-editing appears to be a present-day reality for a small group of patients with the rare genetic condition known as hereditary angioedema (HAE).” Interim results “from a...

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Analysis Finds Higher Uptake Of Pediatric COVID-19 Vaccinations, Boosters Could Prevent Thousands Of Hospitalizations, Lost School Hours

CNN (11/15, McPhillips) reports, “Higher Covid-19 vaccination rates among US children could prevent thousands of pediatric hospitalizations and millions of missed school days, according to an analysis published Tuesday by the Commonwealth Fund and the Yal...

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Over Half Of Patients Still Experience At Least One Post-COVID-19 Symptom Two Years After Acute Infection Regardless Of Hospitalization, Study Shows

MedPage Today (11/15, Hein) reports, “Over half of patients were still experiencing at least one post-COVID-19 symptom 2 years after acute infection, whether they had been hospitalized or not, a cross-sectional cohort study showed.” Among the “nearly 700...

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Repeated Influenza Vaccination May Attenuate Some Effectiveness Of Vaccine Protection Against Certain Influenza Strains, Research Indicates

Infectious Disease Advisor (11/15, Nye) reports research indicates that “repeated influenza vaccination may attenuate some effectiveness of vaccine protection against certain influenza strains.” The findings of the 83-study systematic review and 41-study...

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Married Women Less Likely To Receive STI Counseling, HIV Testing During Year Before Pregnancy Compared To Unmarried Women, Research Suggests

Healio (11/15, Michael) reports “married women are less likely to receive sexually transmitted disease counseling and HIV testing in the year before a pregnancy compared with unmarried women, according to research presented at ID Week 2022.” Out of “the 1...

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Physicians Seeing Uptick In RSV Among Older Adults

CNN (11/15, Christensen) reports, “The respiratory virus season has started early in kids this year and flooded children’s hospitals in many parts of the country – especially with respiratory syncytial virus, known as RSV.” With “more kids getting RSV, th...

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Two Rapid Diagnostic Testing Methods Appear To Have High Sensitivity, Specificity For Diagnosing Ebola Virus Disease, Systematic Review Suggests

Infectious Disease Advisor (11/14, Lopez) reports, “Two rapid diagnostic testing methods were found to have high sensitivity and specificity for diagnosing Ebola virus disease (EVD), according to” a 15-study systematic review; 10 studies “assessed lateral...

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Clinical And Cycle Threshold Value Assessment Fails To Identify 33% Of Genomically Supported COVID-19 Reinfections In Study

Healio (11/14, Stulpin) reports, “Although clinical and cycle threshold value assessment can distinguish COVID-19 reinfection from detecting virus from a prior infection, it failed to identify 33% of genomically supported reinfections, according to a...st...

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Moderna Bivalent COVID-19 Booster Generates Higher Levels Of Neutralizing Antibodies Against Omicron Subvariants Than Previous Booster, Study Indicates

The New York Times (11/14, LaFraniere) reports a study “by Moderna suggests that its updated coronavirus booster strengthens a key component of the immune system’s defense against the Omicron subvariant that accounted for most infections in the United Sta...

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COVID-19 Monoclonal Antibody Treatment Safe For Pregnant Patients But Not That Effective, Study Finds

MedPage Today (11/14, D'Ambrosio) reports “monoclonal antibody treatment for COVID-19 was safe to use in pregnancy, but wasn’t all that effective, according to a single-center study” published in the Annals of Internal Medicine. Among pregnant patients wh...

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Metabolomics: A New Tool to Reveal the Nature of Diabetic Kidney Disease

3 Questions with Marsha Kinney, MD, MASCP

Cases Of Omicron Subvariants BQ.1.1, BQ.1 In US Surpass BA.5, Data Show

Seroconversion To HIV Positivity During Dapivirine Vaginal Ring Use Does Not Increase Risk For Poor Outcomes Of Subsequent ART In Women, Analysis Finds

In Children Exposed To TB, Chest Radiography May Help In Detecting Asymptomatic Coprevalent TB, Predicting Incident TB After Baseline, Research Suggests

No Association Detected Between COVID-19 Vaccination, Herpes Zoster Infection In Study

Drugmakers Struggle To Keep Up With Coronavirus Mutations

WHO Director-General Expects First Ebola Vaccine Doses To Arrive In Uganda Next Week

Haiti’s Cholera Situation Worsening As COVID-19 Cases Increase In The Americas, PAHO Says

FDA Issues EUA To Roche’s Monkeypox Test

Single Infusion Of CRISPR/Cas9-Based Treatment Appears Safe In Patients With Hereditary Angioedema, Interim Trial Results Suggest

Analysis Finds Higher Uptake Of Pediatric COVID-19 Vaccinations, Boosters Could Prevent Thousands Of Hospitalizations, Lost School Hours

Over Half Of Patients Still Experience At Least One Post-COVID-19 Symptom Two Years After Acute Infection Regardless Of Hospitalization, Study Shows

Repeated Influenza Vaccination May Attenuate Some Effectiveness Of Vaccine Protection Against Certain Influenza Strains, Research Indicates

Married Women Less Likely To Receive STI Counseling, HIV Testing During Year Before Pregnancy Compared To Unmarried Women, Research Suggests

Physicians Seeing Uptick In RSV Among Older Adults

Two Rapid Diagnostic Testing Methods Appear To Have High Sensitivity, Specificity For Diagnosing Ebola Virus Disease, Systematic Review Suggests

Clinical And Cycle Threshold Value Assessment Fails To Identify 33% Of Genomically Supported COVID-19 Reinfections In Study

Moderna Bivalent COVID-19 Booster Generates Higher Levels Of Neutralizing Antibodies Against Omicron Subvariants Than Previous Booster, Study Indicates

COVID-19 Monoclonal Antibody Treatment Safe For Pregnant Patients But Not That Effective, Study Finds