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Patients With Alpha Coronavirus Variant Do Not Carry More Virus In Upper Respiratory Tract, Data Indicate

Healio (6/30, Stulpin) reports, “Patients with the alpha variant of SARS-CoV-2 do not carry more virus in their upper respiratory tract despite increased transmissibility, according to” researchers who evaluated “if patients had higher viral loads and, co...

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Serum miRNA Differentially Contributes To Asthma Pathogenesis In Patients 65 Years And Older, Study Says

Pulmonology Advisor (6/30, Schad) reports, “Serum microRNA (miRNA) may differentially contribute to asthma pathogenesis in older (> 65 years old) vs younger (30 to 50 years old) patients, according to” findings from a 59-patient study (6/10, Wardzyńska) p...

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Gene Variant Could Be Driving High Rates Of Unnecessary Bone Marrow Biopsies In Black Patients, Researchers Say

HealthDay (6/30, Preidt) reports that “a gene variant may be driving high rates of unnecessary bone marrow biopsies in Black Americans, researchers say.” This “variant is responsible for lower white blood cell levels in some healthy Black people, the inve...

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Immunogenicity Of Bivalent, Quadrivalent HPV Vaccines Correlated To Cross-Protective Efficacy, Study Indicates

Infectious Disease Advisor (6/30, Aghjayan) reports, “Immunogenicity of bivalent and quadrivalent human papillomavirus (HPV) vaccines are correlated to their cross-protective efficacy, with significant differences in induced antibody concentrations 2 to 1...

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Large-Scale Drug Price Increases For Antiparasitic Medication Associated With Higher Outpatient Treatment Costs, Researchers Say

Healio (6/25, Dreisbach) reports large-scale drug price rises “for antiparasitic medication were associated with increased total outpatient treatment costs, or TOCs, researchers” concluded in a cross-sectional study on “the association between antiparasit...

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Low-Dose VBI-2601 Vaccine Safe, Effective In Patients With Chronic Hepatitis B, Results Suggest

Healio (6/30, Marabito) reports, “A treatment regimen of low dose VBI-2601 (BRII-179) injections in patients with chronic hepatitis B exhibited positive safety, tolerability and efficacy, according to” findings presented during the International Liver Con...

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CureVac’s Vaccine Just 48% Effective Against COVID-19, Final Phase 3 Trial Results Show

The New York Times (6/30, Zimmer) reports CureVac on Wednesday issued “the final results of its late-stage vaccine trial, confirming earlier data showing that its” COVID-19 vaccine candidate “is far less protective than other vaccines,” reaching “an effic...

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Moderna COVID-19 Vaccine Produces Antibodies Against Delta Variant, Preprint Study Suggests

Reuters (6/29, Roy) reports Moderna’s COVID-19 vaccine “showed promise against the Delta” coronavirus variant “in a lab study, with a modest decrease in response compared to the original strain.” The study “was conducted on blood serum from eight particip...

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Test Restriction Intervention More Effective Than EHR-Based Support In Reducing C. Diff Testing, Research Suggests

Healio (6/29, Stulpin) reports, “An intervention that required administrative approval of all Clostridioides difficile [C. Diff] testing after hospital day 3 out-performed electronic health record-based support in reducing C. difficile testing,” researche...

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Fidaxomicin More Effective Than Metronidazole, Vancomycin For C. Diff Shedding Reduction, Study Says

Infectious Disease Advisor (6/29, Nye) reports trial results published in Clinical Infectious Diseases showed that Clostridioides difficile (C. diff) shedding was “more effectively reduced with fidaxomicin therapy compared with vancomycin and metronidazol...

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Fostemsavir Tied To Sustained Virologic Response In Heavily Treatment-Experienced HIV-1, Results Show

Infectious Disease Advisor (6/29, Lee) reports fostemsavir therapy “in heavily treatment-experienced patients with HIV-1 was found to be associated with sustained virologic response rates through 96 weeks of treatment, according to” phase 3 clinical findi...

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Researchers Recommend Novel Definition For Extensively Drug-Resistant Tuberculosis

Pulmonology Advisor (6/29, Alvarez) reports a recent study published in the American Journal of Respiratory and Critical Care Medicine “suggested a new definition of extensively drug-resistant tuberculosis (XDR-TB) as multidrug resistant (MDR) plus additi...

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Rhode Island Resident Diagnosed With Powassan Virus Disease

The AP (6/29) reports that on Tuesday, a healthy Rhode Island resident, who is over the age of 70, has been diagnosed with Powassan virus disease, “a rare tick-borne disease that can cause muscular weakness or even paralysis.” The CDC confirmed the case,...

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CCTA Detects Higher Incidence Of Coronary Plaque Among HIV-Positive People Despite Cardiovascular Disease Risk, Study Indicates

Aunt Minnie (6/29, Madden Yee) reports “coronary CT angiography (CCTA) shows that HIV-positive people have higher incidence of coronary plaque – even if they are at low to moderate risk for cardiovascular disease,” research suggests. The study published i...

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US COVID-19 Contact Tracers Seeking To Track Delta Variant Spread

The Wall Street Journal (6/29, McKay, Subscription Publication) examines the efforts of US COVID-19 contact tracers as active infections continue to plummet throughout the country even as the Delta variant is expected to spread. State COVID-19-tracking ef...

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Pfizer-BioNTech, Moderna COVID-19 Vaccines Likely Provide “Vast Majority” Of Recipients With Long-Term Immunity, Researchers Say

The New York Times (6/28, Mandavilli) reports a new study published in Nature has found the COVID-19 vaccines from Pfizer-BioNTech and Moderna “set off a persistent immune reaction in the body that may protect against the coronavirus for years, scientists...

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Rectal, Stool Samples Detect Enteropathogens In Children With Isolated Vomiting, Study Says

Infectious Disease Advisor (6/28, Mermelstein) reports, “Rectal swabs and stool samples identified an enteropathogen in more than half of children who presented with isolated vomiting, and nearly one-third of the pathogens were noroviruses, according to”...

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Treatment With Low-Dose Azithromycin For Chronic Cough In Patients With Idiopathic Pulmonary Fibrosis Did Not Significantly Improve Cough-Related Quality Of Life, Study Finds

Healio (6/28, Welsh) reports, “Treatment with low-dose azithromycin for chronic cough in patients with idiopathic pulmonary fibrosis did not significantly improve cough-related quality of life, severity or frequency compared with placebo.” This “randomize...

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Delta Coronavirus Variant Surge Prompts New Restrictions Worldwide

The Washington Post (6/28, Cunningham) reports, “The rapid spread of the delta coronavirus variant has forced a growing number of countries to reimpose lockdowns and other public health restrictions, raising fears that the more contagious variant was hamp...

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On-Site PrEP Access Cuts HIV Incidence By Half, Study Finds

Healio (6/24, Dreisbach) reports, “On-site access to PrEP during a clinical trial reduced HIV incidence by around 50%,” researchers concluded in a “time-series study of 2,124 women from South Africa from nine sites where access to oral PrEP was initiated...

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Patients With Alpha Coronavirus Variant Do Not Carry More Virus In Upper Respiratory Tract, Data Indicate

Serum miRNA Differentially Contributes To Asthma Pathogenesis In Patients 65 Years And Older, Study Says

Gene Variant Could Be Driving High Rates Of Unnecessary Bone Marrow Biopsies In Black Patients, Researchers Say

Immunogenicity Of Bivalent, Quadrivalent HPV Vaccines Correlated To Cross-Protective Efficacy, Study Indicates

Large-Scale Drug Price Increases For Antiparasitic Medication Associated With Higher Outpatient Treatment Costs, Researchers Say

Low-Dose VBI-2601 Vaccine Safe, Effective In Patients With Chronic Hepatitis B, Results Suggest

CureVac’s Vaccine Just 48% Effective Against COVID-19, Final Phase 3 Trial Results Show

Moderna COVID-19 Vaccine Produces Antibodies Against Delta Variant, Preprint Study Suggests

Test Restriction Intervention More Effective Than EHR-Based Support In Reducing C. Diff Testing, Research Suggests

Fidaxomicin More Effective Than Metronidazole, Vancomycin For C. Diff Shedding Reduction, Study Says

Fostemsavir Tied To Sustained Virologic Response In Heavily Treatment-Experienced HIV-1, Results Show

Researchers Recommend Novel Definition For Extensively Drug-Resistant Tuberculosis

Rhode Island Resident Diagnosed With Powassan Virus Disease

CCTA Detects Higher Incidence Of Coronary Plaque Among HIV-Positive People Despite Cardiovascular Disease Risk, Study Indicates

US COVID-19 Contact Tracers Seeking To Track Delta Variant Spread

Pfizer-BioNTech, Moderna COVID-19 Vaccines Likely Provide “Vast Majority” Of Recipients With Long-Term Immunity, Researchers Say

Rectal, Stool Samples Detect Enteropathogens In Children With Isolated Vomiting, Study Says

Treatment With Low-Dose Azithromycin For Chronic Cough In Patients With Idiopathic Pulmonary Fibrosis Did Not Significantly Improve Cough-Related Quality Of Life, Study Finds

Delta Coronavirus Variant Surge Prompts New Restrictions Worldwide

On-Site PrEP Access Cuts HIV Incidence By Half, Study Finds