Release Date: May 2017
MOC: PC, MK, PBL
Christopher A. Tormey, MD
Medical Director of the Transfusion Service, VA Connecticut Healthcare System, West Haven, CT; Associate Professor of Laboratory Medicine, Yale University School of Medicine, New Haven, CT
Blood group alloantibodies remain a highly important issue to blood banks and transfusion services as alloimmunization to blood group antigens is associated with delays in providing compatible products to patients, and can contribute to increased patient morbidity and mortality. One of the main problems associated with blood group antibodies is the challenge of identification in the transfusion laboratory. In this session, we will review recent data regarding three of the principal obstacles to blood group antibody detection (evanesce; record fragmentation; missed alloimmunization) and discuss strategies blood banks can use to try and combat these challenges.
After attending this session, participants will be able to:
· Identify clinical problems, including morbidity and mortality, associated with blood group antigen alloimmunization.
· Discuss three principal challenges in detecting blood group antibodies that may contribute to their association with morbidity and mortality.
· Review potential solutions to increase detection of blood group antibodies and to mitigate the clinical impact of alloimmunization.
Who should attend? Practicing Pathologists, Residents, Laboratory Managers, Bench Supervisors, Bench Technologists & Technicians, Students