Back to Society of Hematopathology Quarterly Case Winter 2016: Primary myelofibrosis with an unusual MPL mutation: Integrating molecular testing into the diagnosis and prognosis of BCR-ABL1 negative myeloproliferative neoplasms.
Intended Audience: Pathologists, Residents, and Laboratory Professionals
Upon completion of this activity, you will be able to:
• contrast the morphologic characteristics of polycythemia vera, essential thrombocythemia, and primary myelofibrosis.
• describe the characteristic driver mutations and the mutational landscape of distinct myeloproliferative neoplasms.
• utilize clinical, morphologic, and molecular characteristics to correctly diagnose and risk-stratify patients with myeloproliferative neoplasms.
• design a rational clinical, morphologic, and molecular diagnostic approach to myeloproliferative neoplasms.