Molecular Surgical Pathology for the Practicing Pathologist

Educational Course:

Molecular pathology offers unparalleled opportunities for quick screening for disease-associated mutations and pharmacogenetic predictors of response to specific therapies. This course will provide an in-depth introduction to the new world of molecular pathology testing, including the tools for screening molecular variables and the relevance of those variables to patient care.

The expert faculty will use cases to introduce molecular concepts and terminology, describe the molecular workup, and discuss the reporting of molecular tests. You’ll hear about molecular subsets and HER2 testing guidelines for breast carcinoma, the molecular basis of hemochromatosis, molecular and cytogenetic testing in lymphomas and leukemias, and many other cutting-edge topics.

You’ll also get advice about setting up a molecular lab and bringing in new tests, which tests to send out, validating in-lab assays, and achieving compliance in an evolving regulatory environment. Plus, you’ll learn how to integrate molecular pathology data into your diagnostic process and report that data so that clinicians can understand the significance.

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Faculty
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Following this course, you will be able to:

Integrate concepts, terminology, indications, and applications of molecular pathology into your practice.
Use molecular pathology tests to improve the accuracy of your morphologic diagnosis.
Assess differences in disease pathogenesis based on molecular pathology test results.
Identify molecular subsets relevant to disease natural history and patient response to customized therapies.
Determine which tests to bring in or send out.
Formulate a plan to validate new in-lab assays.
Advise treating clinicians regarding the significance of molecular test results

Core competencies: PC, MK, ICS, PBL, PR, SBP

Feature: Audience Response System

Course Fee:

List Price:                     $1299
Member Price:               $999
Residents:                     $500

Cancellation Policy: A full refund will be issued for cancellations received in writing no later than one week prior to the start date of the meeting. Refunds are not issued for cancellations received after that date. ASCP reserves the right to cancel a program due to circumstances beyond its control or for insufficient registration. Registrants will be notified immediately and allowed to substitute a session or obtain a full refund. The Society is not responsible for penalties incurred as a result of cancelled transportation. For further information, contact ASCP Customer Service at 800.267.2727, option 2; international callers: 312.541.4890; or www.ascp.org/feedback.

Director:

William K. Funkhouser, MD, PhD, FASCP
University of North Carolina at Chapel Hill

Faculty:

Todd S. Barry, MD, PhD, FASCP
Clarient Diagnostic Services

Margaret L. Gulley, MD
University of North Carolina at Chapel Hill

The Francis Marion Hotel
387 King Street
Charleston, SC 29403

Telephone: (843) 937-8691
Website: www.francismarionhotel.com

The Francis Marion Hotel in Charleston has been at the heart of the city’s social, business, and community life since opening in 1924. Meticulously restored in 1996 with a $12 million National Trust for Historic Preservation Award-winning restoration, the Francis Marion Hotel now combines 1920′s style and grace with 21st Century comfort and convenience in the heart of historic Charleston. Don’t miss the antebellum homes, magnificent gardens, antique shops and boutiques, and world-class restaurants, all within easy walking distance of the hotel.

Reserve your room by March 22, 2013, and mention ASCP/Molecular Pathology to receive the special room rate of $164 single/double per night, plus applicable taxes. Availability is limited so be sure to book early! Room rate includes complimentary wireless or wired Internet in guest rooms.

Ground Transportation:

Shuttle: $12 one way (subject to change)
Taxi: $26-30 one way (subject to change)

Monday, April 15

8:00am–11:50 am

Welcome and Introduction

William K. Funkhouser, MD, PhD, FASCP

ISH, Cytogenetics, Arrays, Nomenclature

Margaret L. Gulley, MD

DNA Amplification Methods

Todd S. Barry, MD, PhD, FASCP

DNA Sequencing, Mutation Analysis

William K. Funkhouser, MD, PhD, FASCP

Case1: Breast Carcinoma I

Margaret L. Gulley, MD

1:10 – 5:00 pm

Case 2: Breast Carcinoma II

Todd S. Barry, MD, PhD, FASCP

Case 3: Colorectal Carcinoma: DNA Mismatch Repair Analysis

William K. Funkhouser, MD, PhD, FASCP

Case 4: Viral Biomarkers

Margaret L. Gulley, MD

Case 5: Lymphomas: Chromosomal Translocations and Gene Expression Profiling

Todd S. Barry, MD, PhD, FASCP

Tuesday, April 16

8:00–11:50 am

Case 6: CML and AML

Margaret L. Gulley, MD

Case 7: Patient Identity Testing

William K. Funkhouser, MD, PhD, FASCP

Case 8: Urothelial Carcinoma

Todd S. Barry, MD, PhD, FASCP

Case 9: PTLD

Margaret L. Gulley, MD

1:10 – 5:00 pm

Case 10: Non-small Cell Lung Carcinoma - EGFR

William K. Funkhouser, MD, PhD, FASCP

Case 11: Colorectal Carcinoma: EGFR

Todd S. Barry, MD, PhD, FASCP

Case 12: Myeloproliferative Disorders – JAK2

Margaret L. Gulley, MD

Case 13: Hemochromatosis

William K. Funkhouser, MD, PhD, FASCP

Wednesday, April 17

8:00 – 11:50 am

Case 14: Medullary Thyroid Carcinoma

William K. Funkhouser, MD, PhD, FASCP

Case 15: Sarcomas

Margaret L. Gulley, MD

Case 16: Melanoma - BRAF

Todd S. Barry, MD, PhD, FASCP

Case 17: Clear Cell Renal Carcinoma

William K. Funkhouser, MD, PhD, FASCP

1:10–5:00pm

What Tests to Bring In, What Tests to Send Out

Todd S. Barry, MD, PhD, FASCP

Validating a Molecular Assay

Margaret L. Gulley, MD

Regulatory Environment, CAP Checklists

Todd S. Barry, MD, PhD, FASCP

How to Report Molecular Tests

Margaret L. Gulley, MD

Molecular Surgical Pathology for the Practicing Pathologist

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