Lymphoid Disorders in Blood and Bone Marrow in Children and Adults

Course Author:
Kathyrn Foucar, MD, FASCP
Vice Chair for Clinical Affairs, Director of Hematopathology for the Department of Pathology, and Professor of Pathology at the University of New Mexico, Albuquerque, NM

MOC^[?]: MK
Intended Audience: Pathologists, Residents, Doctoral Scientists,Pathologist Assistants, Medical Technologists, Medical Laboratory Technicians, Students

As hematology laboratory staff members play an important patient-care role in assessing abnormal lymphoid populations, this eCourse offers a comprehensive discussion of identifying, reviewing and assessing blood and bone marrow lymphoid disorders.

It is often a challenge for staff to review abnormal blood smears containing increased numbers of lymphocytes or morphologically abnormal lymphoid cells. Pediatric patients provide a particular challenge in that immature-appearing lymphoid cells are physiologically normal in this age range. In this eCourse, normal ranges by morphological features and predicted immunophenotype of lymphoid cells in blood and bone marrow are presented in order to approach these disorders in a logical algorithmic fashion. This provides a framework for determining when a lymphoid population in blood and bone marrow is abnormal. Clues to identifying physiologically normal and neoplastic processes are also discussed along with a practical approach for the application of more specialized testing. The various causes of reactive lymphocytosis in children and adults are reviewed along with key features useful in distinguishing a reactive lymphocytosis from a neoplastic disorder.

The various causes of reactive lymphocytosis in children and adults are reviewed along with key features useful in distinguishing a reactive lymphocytosis from a neoplastic disorder.

The ASCP designates these educational activities for a maximum of 2 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activities.

These activities meet MOC Part II Lifelong Learning requirements. These activities meet MOC Part II Self-Assessment Module requirements.

ASCP designates these activities for a maximum of 2 CMLE credits. These activities meet CMP and state licensure requirements for laboratory personnel.