Laboratory Methods for Colorectal Cancer Screening

Course Authors:
Saud S. Rahman, MD
Chief Resident in Pathology

Richard A. McPherson, MD
Department of Pathology, Virginia Commonwealth University
Richmond, Virginia

Upon completion of this activity, you will be able to:

• list the current American Cancer Society (ACS) recommendations for colorectal cancer screening.
• delineate the available noninvasive laboratory methods for colorectal cancer screening.
• differentiate the mechanisms behind guaiac-based fecal occult blood testing (G-FOBT) and immunochemical-based fecal occult blood testing (I-FOBT).
• explain the molecular basis of fecal DNA testing.
• recognize the advantages and disadvantages of each available laboratory method for colorectal cancer screening.

The ASCP is accredited by the ACCME to provide CME for physicians. The ASCP designates this educational activity for a maximum of 1 of AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

ASCP designates this activity for a maximum of 1 CMLE credit. This activity meets CMP and state licensure requirements for laboratory personnel.