Online Case Studies

Confounding Antibody Identification: Don’t Forget the Obvious

This is an online activity in Transfusion Medicine that identifies anti-P1 at 37°C and/or at the anti-human globulin phase as a single antibody or in conjunction with other antibodies and offers 1.0 continuing education (CME/SAM/CMLE) credit that can be used to fulfill MOC Part II and CMP requirements

Neonatal Alloimmune Thrombocytopenia, Assuring Timely Diagnosis and Treatent

This is an online activity in Transfusion Medicine that describes the common clinical presentation of neonatal alloimmune thrombocytopenia (NAIT) and offers 1.0 continuing education (CME/SAM/CMLE) credit that can be used to fulfill MOC Part II and CMP requirements

Q Fever Over 75 Years: What Have We Achieved?

This is an online activity in Microbiology that discuss the history and epidemiology of Q fever and offers 1.0 continuing education (CME/SAM/CMLE) credit that can be used to fulfill MOC Part II and CMP requirements.

Trichosporon Species: Classification, Identification, and Clinical Relevance

This is an online activity in Microbiology that describes the types of infections associated with Trichosporon spp and offers 1.0 continuing education (CME/SAM/CMLE) credit that can be used to fulfill MOC Part II and CMP requirements.

Primary Mediastinal (Thymic) Large B-Cell Lymphoma

This is an online activity in Hematology that summarizes the clinical features of primary mediastinal large B-cell lymphoma and offers 1.0 continuing education (CME/SAM/CMLE) credit that can be used to fulfill MOC Part II and CMP requirements.

Anaplastic Large-Cell Lymphoma, Alk-Positive

This is an online activity in Hematology that describes the clinical and morphologic features of anaplastic large-cell lymphoma, anaplastic lymphoma kinase–positive (ALCL, ALK+) and offers 1.0 continuing education (CME/SAM/CMLE) credit that can be used to fulfill MOC Part II and CMP requirements.

Ocular Proliferations in the Context of Cytologic Evaluation

This is an online activity in Cytopathology that describes how clinical ophthalmologists sample lesions of the ocular adnexae and offers 1.0 continuing education (CME/SAM/CMLE) credit that can be used to fulfill MOC Part II and CMP requirements.

Discriminating Hepatocellular Carcinoma From Metastatic Adenocarcinoma: The Utility of the Immunocytochemical Panel

This is an online activity in Cytopathology that presents a working approach for the interpretation of malignant and benign mass lesions on fine-needle aspiration biopsies of the liver and offers 1.0 continuing education (CME/SAM/CMLE) credit that can be used to fulfill MOC Part II and CMP requirements.

Application of Point-of-Care Measurement of Creatinine

This is an online activity in Clinical Chemistry that identifies patient risk factors associated with contrast agent–associated nephrotoxicity and offers 1.0 continuing education (CME/SAM/CMLE) credit that can be used to fulfill MOC Part II and CMP requirements.

Chagas Disease: A Potential Concern for Transfusion and Transplantation in the United States

This is an online activity in Transfusion Medicine that describes the areas within North America that have high rates of seroprevalence for Chagas disease and offers 1.0 continuing education (CME/SAM/CMLE) credit that can be used to fulfill MOC Part II and CMP requirements.

Plasma Cell Myeloma (Multiple Myeloma)

Evaluating Errors in Cytologic-Histologic Correlation: A Practical Application of Root-Cause Analysis

Primary Malignant Mesothelioma of the Pericardium: An Overview

Mixed Epithelial and Stromal Tumor of the Kidney

Detection of Gram-Negative Bacteria Producing Newer Types of ß-Lactamases

Dural Sinus Thrombosis

Cytopathology of Osteosarcoma

The Laboratory and the Poisoned Patient

Human Allografts and the Transfusion Service

Small Cell Neuroendocrine Carcinoma of the Cervix

Mesenchymal Hamartoma of the Chest Wall

This is an online activity in Surgical Pathology that describes the epidemiology and clinical features of chest wall amartoma of infancy and offers 1.0 continuing education (CME/SAM) credit that can be used to fulfill MOC Part II and CMP requirements.

A Spectrum of Presentations in Cardiac Amyloidosis

T-Cell/Histiocyte-Rich Large B-Cell

Cytologic Features of Hyalinizing

Renal Function Testing

Infantile Myofibromatosis/ Hemangiopericytoma

Transfusion Issues in Cold Agglutinin Disease

Corynebacterium Amycolatum: An Opportunistic Pathogen

Lymphoplasmacytic Lymphoma and Waldenström Macroglobulinemia

CNS Heterotopia and Diogenes Syndrome

Intraoperative Cytology of Granulosa Cell Tumors of the Ovary

Histologic Presentation of a Two- and Three-Vessel Umbilical Cord: A Potential Case of Fused Umbilical Arteries

This is an online activity in Surgical Pathology that discuss the significance of fused umbilical arteries as it applies to the congenital anomaly rate in newborns and offers 1.0 continuing education (CME/SAM) credit that can be used to fulfill MOC Part II and CMP requirements

Myeloid Sarcoma of the Vulva: An Unexpected Tumor

Pulmonary Adenocarcinoma, Micropapillary Pattern

Staphylococcus Saccharolyticus: A Rare but Important Cause of Anaerobic Endocarditis

Identifying Injuries Associated With Airbag Deployment

Bile Duct Brush Cytology Of Non-Hodgkin Lymphoma

Osteoporosis and Bone Markers

Refractory Cytopenia With Multilineage Dysplasia and Ringed Sideroblasts

Autologous Transfusion Practices

Sporadic Microsatellite Instability-High Colon Carcinoma with hMLH-1 Promoter Methylation

Hepatocellular Carcinoma and Tumor Markers

Differential Diagnosis and Workup of Myxoid Adipocytic Tumors of the Retroperitoneum

This is an online activity in Surgical Pathology that describes the spectrum of adipocytic tumors of the retroperitoneum and offers 1.0 continuing education (CME/SAM) credit that can be used to fulfill MOC Part II and CMP requirements.

Oncocytic/Hürthle Cell Lesions of the Thyroid

Lethal Varicella Pneumonia

Minimizing Blood Transfusions in Medicine and Surgery: Current Considerations

Cutaneous Cryptococcosis

Ochrobactrum Infections

Factor XI Deficiency

Coxsackie B Viral Infection With Myocarditis

Cytologic Diagnosis of Lymphoid Lesions of the Thyroid Gland

Laboratory Methods for Colorectal Cancer Screening

Drug-Induced Immune Hemolytic Anemia

Algae Gone Wild: When Plants Become Pathogens

This is an online activity in Microbiology that describes the microscopic and biochemical characteristics of Prototheca wickerhamii that differentiate it from Prototheca zopfii and offers 1.0 continuing education (CME/SAM/CMLE) credit that can be used to fulfill MOC Part II and CMP requirements.

Large Cell Neuroendocrine Carcinoma of the Lung: Pathological Assessment and Differential Diagnoses of Neuroendocrine Carcinomas

Cellular Mesoblastic Nephroma

Septic Arthritis in Patients With Systemic Lupus Erythematosus

Juvenile Myelomonocytic Leukemia

Suicidal Asphyxiation by Helium Intoxication and Plastic Bag Suffocation

Xanthogranulomatous Pyelonephritis: An Important Lesion in the Differential Diagnosis of Renal Cell Carcinoma

Diagnosis of Secondary Follicular Center Cell Lymphoma to Pancreas With Endoscopic Ultrasound–Guided Fine-Needle Aspiration Biopsy

A Primer on Antiphospholipid Syndrome

Cutaneous Spindle Cell Neoplasms

Clear Cell Sarcoma of Tendons and Aponeuroses: A Review with Discussion of Molecular Techniques in Diagnosis

A Case of Intracellular Red Blood Cell Parasites

This is an online activity in Hematology that describes the clinical manifestations of babesiosis and offers 1.0 continuing education (CME/SAM/CMLE) credit that can be used to fulfill MOC Part II and CMP requirements.

Rat Bite Fever and Haverhill Fever Due to Streptobacillus moniliformis: Recognition of the Clinical Syndromes, Laboratory Diagnosis, and Treatment

Hypereosinophilic Syndrome/Chronic Eosinophilic Leukemia: Clinical and Pathologic Features

Hirsutism and Hyperandrogenism

Clinical and Pathologic Manifestations of Congenital Ichthyosiform Disorders

Transfusion Evaluation and Management of Patients with IgA Deficiency

An Unusual Dural-Based Tumor

Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: Clinical and Pathological Features

The Role of Fine-Needle Aspiration Biopsy In Diagnosis of Pulmonary Fungal Infections

Indirect Phlebotomy: Is It Good Practice?

A 16-Year-Old Female With Maxillary Sinus Mass

Fatal Fall of a Nine-Month-Old Infant

This is an online activity in Forensic Pathology that describes the autopsy findings seen in infants and children who have sustained inflicted head injury and offers 1.0 continuing education (CME/SAM) credit that can be used to fulfill MOC Part II and CMP requirements.

Chondrosarcoma: Clinical and Pathologic Features

Cryptococcus Neoformans Var Gattii: Changing Epidemiology in an Emerging North American Pathogen

Understanding Status Asthmaticus

Cytopathology of Adrenal Lesions in the Adult Patient

Fine-Needle Aspiration of Abdominal Masses in Young Women

The Biochemical Diagnosis of Pheochromocytoma

Living Forensic Examination of a Strangulation Victim

Acquired Platelet Disorders

Central Giant Cell Granuloma: An Overview of Multinucleated Giant Cell Lesions of the Bone

Biliary Brush Cytologic Diagnosis With FISH Correlation

This is an online activity in Cytopathology that describe the range of abnormalities observed in biliary specimens examined with FISH and offers 1.0 continuing education (CME/SAM/CMLE) credit that can be used to fulfill MOC Part II and CMP requirements.

Bacillus Bacteremia

Sickle Cell Disease

Diagnosis of Sarcoidosis in a Mediastinal Lymph Node Using EUS-Guided FNA

Granulocyte Transfusions

Cellular Fibroma of the Ovary

Hemoglobin A1c and Estimated Average Glucose Levels

This is an online activity in Clinical Chemistry that describe those populations in which further research of eAG is needed and offers 1.0 continuing education (CME/SAM/CMLE) credit that can be used to fulfill MOC Part II and CMP requirements.

Fetal Lung Maturity Testing

Aeromonas spp and Diarrheal Diseases: Is there an association

Mucoepidermoid Carcinoma, Oncocytic Type

This is an online activity in Surgical Pathology that discuss the common types of oncocytic salivary gland neoplasms and offers 1.0 continuing education (CME/SAM) credit that can be used to fulfill MOC Part II and CMP requirements.

Asphyxiation Following Inhalation of Cat Litter

Gastrointestinal Stromal Tumors: Cytologic Spectrum and Differential Diagnosis

Alkaline Phosphatase Isoenzyme Analysis: Guiding the Differential Diagnosis of Elevated Serum Total Alkaline Phosphates

To Bleed or Not To Bleed...Which Factor VIII Assays To Use

Genetic Evaluation of Aortic Dissections

Primary Effusion Lymphoma (PEL)

Evaluation of Testicular Borderline Serous Tumors

Internal Iliac Vein Leiomyosarcoma

Laboratory Diagnosis of Influenza

ALK+ Diffuse Large B-Cell Lymphoma, Plasmablastic Type

Malignant Mesothelioma and Extrapleural Pneumonectomy

This is an online activity in Surgical Pathology that discuss the implications of the diagnosis of mesothelioma and offers 1.0 continuing education (CME/SAM) credit that can be used to fulfill MOC Part II and CMP requirements.

Peripartum Deaths and Cardiovascular Disease

Insular Thyroid Carcinoma: Difficulties on Fine-Needle Aspiration Cytology and its Diagnostic Importance

Secretory Breast Carcinoma

This is an online activity in Surgical Pathology that explains the epidemiology of secretory breast carcinoma (SBC) and offers 1.0 continuing education (CME/SAM) credit that can be used to fulfill MOC Part II and CMP requirements.

West Nile Virus

Small Cell Carcinoma of the Endometrium

This is an online activity in Surgical Pathology that discuss the epidemiology and clinical presentation of small cell carcinomas (SCCs) of the female genital tract and offers 1.0 continuing education (CME/SAM) credit that can be used to fulfill MOC Part II and CMP requirements.

Infections Due to Kluyvera Species

This is an online activity in Microbiology that explain the biochemical characteristics of Kluyvera species and differentiate them from other members of the Enterobacteriaceae family and offers 1.0 continuing education (CME/SAM/CMLE) credit that can be used to fulfill MOC Part II and CMP requirements.

Hypereosinophilic Syndrome With Loeffler Endocarditis: Diagnostic Criteria, Characteristic Findings, and Appropriate Laboratory Workup

This is an online activity in Forensic Pathology that explain the pathophysiology that causes the characteristic findings seen in patients with Loeffler endocarditis and offers 1.0 continuing education (CME/SAM) credit that can be used to fulfill MOC Part II and CMP requirements.

Diagnostic Approach to Hyperchromatic Cell Clusters on Conventional and Liquid-Based Papanicolaou Tests

This is an online activity in Cytopathology that describes the differences in cytomorphologic and background changes on conventional versus liquid-based preparations and offers 1.0 continuing education (CME/SAM/CMLE) credit that can be used to fulfill MOC Part II and CMP requirements.

Warfarin Coagulopathy Monitoring and Treatment Strategies

Primary Mucosal Malignant Melanoma of the Head and Neck

This is a CheckSample Continuing Education on-line course. Complete a multiple-choice pretest and post test to earn 1 CME/SAM credit.

Tall Cell Variant of Papillary Thyroid Carcinoma

This is an online activity in Cytopathology that describe the cytologic features of tall cell variant of papillary thyroid carcinoma (TCV-PTC) and offers 1.0 continuing education (CME/SAM/CMLE) credit that can be used to fulfill MOC Part II and CMP requirements.

Axillary Mass in a Middle-Aged Man: Unexpected Diagnosis

This is an online activity in Surgical Pathology that describes the key histomorphologic features of ossifying fibromyxoid tumor of soft parts and offers 1.0 continuing education (CME/SAM) credit that can be used to fulfill MOC Part II and CMP requirements.

Prenatal Diagnosis and Management of Hemolytic Disease of the Fetus and Newborn

This is an online activity in Transfusion Medicine that describes the pathogenic mechanism of hemolytic disease of the fetus and newborn and offers 1.0 continuing education (CME/SAM/CMLE) credit that can be used to fulfill MOC Part II and CMP requirements.

Extranodal Marginal Zone B-Cell Lymphoma of Mucosa-Associated Lymphoid Tissue Involving the Stomach

This is an online activity in Hematology that describes the typical patient with extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) and offers 1.0 continuing education (CME/SAM/CMLE) credit that can be used to fulfill MOC Part II and CMP requirements.

Anaphylaxis: Fatal Hypersensitivity Reaction to Carboplatin

This is an online activity in Forensic Pathology that describes the clinical features and pathomechanism of anaphylaxis and offers 1.0 continuing education (CME/SAM) credit that can be used to fulfill MOC Part II and CMP requirements.

Beckwith-Wiedemann Syndrome: The Role of Molecular Diagnostic Testing in Patient Care

This is an online activity in Clinical Chemistry that describe the typical presentation of a child with Beckwith-Wiedemann syndrome (BWS) and offers 1.0 continuing education (CME/SAM/CMLE) credit that can be used to fulfill MOC Part II and CMP requirements.

Human Papillomavirus and Cervical Cancer Screening

Diagnosis of Bacterial Meningitis at Autopsy

Mantle Cell Lymphoma, Pleomorphic Variant, Involving the Bone Marrow

Mansonella Ozzardi Infection: Potential Inadvertent Diagnosis

Endoscopic Ultrasound–Guided Fineneedle Aspiration of Pancreatic Endocrine Neoplasms: Diagnostic Challenges and the Role of Immunocytochemistry

This is an online activity in Cytopathology that describes the cytomorphologic criteria for pancreatic endocrine neoplasms and offers 1.0 continuing education (CME/SAM/CMLE) credit that can be used to fulfill MOC Part II and CMP requirements.

Cardiomyopathy in Survivors of Childhood Cancers

This is an online activity in Forensic Pathology that discuss the increased morbidity and mortality of survivors of childhood cancers and offers 1.0 continuing education (CME/SAM) credit that can be used to fulfill MOC Part II and CMP requirements.

Anticoagulation Clinic: Point-of-Care Testing

This is an online activity in Clinical Chemistry that explains what the international normalized ratio (INR) is, how it is determined, problems in its determination, and how it is used and offers 1.0 continuing education (CME/SAM/CMLE) credit that can be used to fulfill MOC Part II and CMP requirements.

Acute Hemorrhagic Leukoencephalitis (AHL or Hurst Disease)

Streptococcus Pneumoniae–Induced Hemolytic Uremic Syndrome and T Activation: Pathogenesis and Treatment

Bacterial Detection of Platelets

Adrenal Gland Leiomyosarcoma and Metastasis to the Lung

Radiograph Limitations in the Recovery of Firearm Projectiles With Radiolucent Features

This is a CheckSample Continuing Education on-line course. Complete a multiple-choice pretest and post test to earn 1 CME/SAM credit.

Granular Cell Tumor of the Tongue

This is a CheckSample Continuing Education on-line course. Complete a multiple-choice pretest and post test to earn 1 CME/SAM credit.

Pleomorphic Xanthoastrocytoma in the Right Temporal Lobe

Vitamin K–Deficiency Bleeding in an Infant: Clinical Features and Laboratory Diagnosis

Coccidiodes Infection in a Pediatric Patient

Kikuchi Histiocytic Necrotizing Lymphadenitis

Polypharmacy, Hyperthermia, and Sudden Death

The Recognition of Extrauterine Malignancies in Pap Smears

Thyrotoxicosis and Postmortem Diagnosis of Thyroid Disease

Vitamin D, an Overview

Bile-Duct-Brushing Cytologic Examination

Pleomorphic Rhabdomyosarcoma With Epithelioid Features

Diabetes Mellitus Presenting as Sudden Death

Ovarian Mass in a Postmenopausal Patient With Elevated Serum Inhibin

Salmonella Infection and Its Sequelae

Diagnostic Categories, Criteria, and Follow-Up for Follicular Lesions of the Thyroid

Hepatitis B Reactivation: Old Virus, New Problem

The Partial D Phenotype: Laboratory Diagnosis and Clinical Implications

Acinic Cell Carcinoma Of the Parotid Gland With Metastasis to the Humerus

Invasive Aspergillosis: Update On Diagnosis and Treatment

Clonally Related Histiocytic Neoplasm in Patients With Prior Acute Lymphoblastic Leukemia

Pulmonary Capillary Hemangiomatosis: A Rare Cause Of Pulmonary Hypertension

Reactive Processes Mimicking Adenocarcinoma and Squamous Cell Carcinoma in Respiratory Cytologic Specimens

Insecticide Poisoning By Organophosphates: Pharmacologic Effects and the Laboratory’s Role in Diagnosis

Paroxysmal Cold Hemoglobinuria

Amebic Meningoencephalitis Caused by Balamuthia mandrillaris

Differentiating Glanzmann Thrombasthenia From Other Qualitative Platelet Disorders

Sudden Cardiac Death in Childhood: Histiocytoid Cardiomyopathy

FNA Cytology of Cervical Sympathetic Chain Schwannoma: Differential Diagnosis of a Mass Lesion at the Bifurcation of the Common Cartoid Artery

Clinical and Biochemical Evaluation of Familial Hypercholesterolemia

Extracorporeal Photopheresis

Orbital Aspergillosis Following Surgical Excision of a Maxillary Sinus Squamous Cell Carcinoma

Myelodysplasia With Isolated Thrombocytopenia (Refractory Thrombocytopenia)

A Disseminated Infection in a Neonate

Cytopathologic Diagnosis of Metastatic Renal Cell Carcinoma Using Immunohistochemistry

Monitoring Compliance in Oxycodone Dosing

Synovial Sarcoma and the Differential Diagnosis of Spindle Cell Tumors of the Upper Respiratory Tract

The Diagnostic Challenges of an Incidentally Discovered Abdominal Neoplasm

Contact Lens–Related Keratomycosis

Methamphetamine Mishaps With Anhydrous Ammonia

Metastatic lesions to the Pancreas: Cytopathology and Clinical Implications

Renal Oncocytoma: Fine-Needle Aspiration Cytology and Differential Diagnosis

Variability Among Methods for Measuring Glucose in Whole Blood: The Influence of Hematocrit

Blood Donor Eligibility and Safety

Intrahepatic Bilary Cystadenocarcinoma

Postiradiation Angiosarcoma of the Breast

Developments in the Diagnosis and Therapy of Diagnosis and Therapy of Human Nocardiosis

A 3-Year-Old Girl With a History of Recurrent Bacterial Infections

Sudden Unexplained Death From a Ruptured Giant Basilar Artery Aneurysm

Diagnostic Pitfalls of Inguinal Endometriosis Sampled Via Fine-needle Aspiration

Idiopathic Thrombocytopenic Purpura—Pathogenesis and Treatment

Mucous Gland Adenoma of the Bronchus

Pigmented Spindle Cell Tumor in a Patient With a Neurocutaneous Syndrome

Aggregatibacter actinomycetemcomitans: Taxonomy Changes, Illness, Laboratory Diagnosis, and Treatment

Hairy Cell Leukemia in a Young Man

The Cytologic Diagnosis of Rosai-Dorfman Disease: A Differential Diagnostic Approach

Neuroblastoma

The Medicolegal Investigation of Recreational Diving Deaths

Thrombotic Thrombocytopenic Purpura: Diagnosis, Pathogenesis, and Treatment

Crescentic Glomerulonephritis, Differential Diagnosis

Malaria Diagnosis: Microscope to Molecular