American Society for Clinical Pathology - Flow Cytometry Can Diagnose Classical Hodgkin Lymphoma in Lymph Nodes With High Sensitivity and Specificity

Flow Cytometry Can Diagnose Classical Hodgkin Lymphoma in Lymph Nodes With High Sensitivity and Specificity

Jonathan R. Fromm, MD, PhD
Department of Laboratory Medicine, University of Washington, Seattle

Anju Thomas
Department of Laboratory Medicine, University of Washington, Seattle

Brent L. Wood, MD, PhD
Department of Laboratory Medicine, University of Washington, Seattle

Keywords: Classical Hodgkin lymphoma; Hodgkin disease; Flow cytometry; Antigen expression

Upon completion of this activity, you will be able to:

describe the flow cytometry derived immunophenotype of Hodgkin and Reed Sternberg (HRS) cells in classical Hodgkin lymphoma (CHL).
discuss the phenomenon of T cell–HRS cell rosettes and its influence on the CHL immunophenotyping.
compare and contrast the immunophenotypes in CHL with those seen in anaplastic large cell lymphoma, T cell–rich large B-cell lymphoma, and nodular lymphocyte-predominant Hodgkin lymphoma.
describe how the HRS cells differ immunophenotypically from reactive CD30-positive immunoblasts.

The ASCP designates this educational activity for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation n the activities.

This activity meets MOC Part II Lifelong Learning requirements. A self-assessment option is available for pathologists attending this program to earn SAM credits for Maintenance of Certification, Part II Self-Assessment Modules (MOC-SAM) for part of the course. For MOC brochure, click here.

List Price

$20.00

Member Price

$15.00

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