Michael J. Sanfelippo, MS, MT(ASCP)
Department of Hematology/Coagulation Services, Marshfield Labs, Marshfield Clinic, Marshfield, WI

Veronica B. Tillema, MT(ASCP)
Department of Hematology/Coagulation Services, Marshfield Labs, Marshfield Clinic, Marshfield, WI

Keywords: Fondaparinux; Arixtra; Automated assay; Dade Behring BCS XP

Upon completion of this activity, you will be able to:

• describe the mechanism of anticoagulation by the drug fondaparinux.
• describe the method by which fondaparinux concentration in human plasma is measured.
• explain the difference between the assay for fondaparinux and the heparins, unfractionated and low-molecular-weight.