Pranil Chandra, DO
Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston

Yong Hannah Wen, MD, PhD
Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY

Sandeep Tuli, DO
Department of Radiology, New York University School of Medicine, New York

Bruce G. Raphael, MD
Department of Medicine, New York University School of Medicine, New York

Edward L. Amorosi, MD
Department of Medicine, New York University School of Medicine, New York

L. Jeffrey Medeiros MD
Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston

Sherif Ibrahim, MD, PhD
Department of Pathology, New York University School of Medicine, New York

Keywords: Spleen; Pseudotumor; Postchemotherapy; Xanthomatous histiocytes; Necrosis

Upon completion of this activity, you will be able to:

• recognize the clinical, morphologic, and immunohistochemical features of postchemotherapy histiocyte-rich pseudotumor.
• differentiate postchemotherapy histiocyte-rich pseudotumor from other entities in the differential diagnosis.