Mariam Alsharif, MD
Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis

Stuart E. H. Cameron, MD
Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis

Jo-Anne H. Young, MD
Department of Medicine, University of Minnesota, Minneapolis

Kay Savik, MS
School of Nursing, University of Minnesota, Minneapolis

Jonathan C. Henriksen
Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis

H. Evin Gulbahce, MD
Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis

Stefan E. Pambuccian, MD
Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis

Keywords: Hematopoietic stem cell transplantation; Infectious complications; Fungal infections; Autopsy

Upon completion of this activity, you will be able to:

• define the major fatal complications of hematopoietic stem cell transplantation (HSCT), and in particular the contribution of infections as a cause of death.
• describe the difficulties in the clinical diagnosis and the role of autopsy in the study of invasive fungal infections in HSCT patients.
• define the chronology, time trends, and microbiological spectrum of fatal fungal infections in HSCT recipients and their organ distribution.