American Society for Clinical Pathology
Justification of the Change From 10% to 30% for the Immunohistochemical HER2 Scoring Criterion in Breast Cancer

Yan-Hui Liu, MD
Department of Pathology and Laboratory Medicine, Guangdong General Hospital, Guangzhou, China

Fang-Ping Xu, MD, PhD
Department of Pathology and Laboratory Medicine, Guangdong General Hospital, Guangzhou, China

Jian-Yu Rao, MD
Department of Pathology and Laboratory Medicine, UCLA Medical Center, Los Angeles, CA

Heng-Guo Zhuang, MD
Department of Pathology and Laboratory Medicine, Guangdong General Hospital, Guangzhou, China

Xin-Lan Luo
Department of Pathology and Laboratory Medicine, Guangdong General Hospital, Guangzhou, China

Li Li, MS
Department of Pathology and Laboratory Medicine, Guangdong General Hospital, Guangzhou, China

Dong-Lan Luo, MS
Department of Pathology and Laboratory Medicine, Guangdong General Hospital, Guangzhou, China

Fen Zhang
Department of Pathology and Laboratory Medicine, Guangdong General Hospital, Guangzhou, China

Jie Xu
Department of Pathology and Laboratory Medicine, Guangdong General Hospital, Guangzhou, China

 

Keywords: HER2; Breast cancer; Immunohistochemistry; Fluorescence in situ hybridization

Upon completion of this activity, you will be able to:

  • outline the protocol for the HER2 fluorescence in situ hybridization (FISH) test.
  • describe the difference between Food and Drug Administration and American Society of Clinical Oncology/College of American Pathologists guidelines for the HER2 immunohistochemical scoring system for breast carcinomas.
  • address interpretation of results using different criteria and cite factors that may lead to discordant results between immunohistochemical scoring and FISH for HER2 in breast carcinomas.

This activity meets MOC Part II Lifelong Learning requirements. A self-assessment option is available for pathologists attending this program to earn SAM credits for Maintenance of Certification, Part II Self-Assessment Modules (MOC-SAM) for part of the course.

List Price
$20.00
Member Price
$15.00



Member Login


Store Search
From: 
Email:  
To: 
Email:  
Subject: 
Message: