Robin T. Vollmer, MD
Laboratory Medicine, Veterans Affairs and Duke University Medical Centers, Durham, North Carolina

Keywords: rostate cancer; Percentage of tumor; Survival; Grade; Prostatectomy; Prostate-specific antigen; Serum PSA; Tumor size; Age

Upon completion of this activity, you will be able to:

• define the difference between 2 measures of tumor size in the prostate: absolute tumor volume and percent tumor.
• estimate percent tumor in prostatectomy specimens.
• describe how percent tumor relates to overall survival.
• correlate serum PSA to volumes of benign and tumor tissues, as well as to histologic grade of carcinoma.