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Annabel Maruani, MD
University François Rabelais, Tours, France
Laboratory Ultrasound Signal Instrumentation CNRS FRE 2448, Tours
Department of Dermatology, University Hospital Center of Tours
Marie-Christine Machet, MD
University François Rabelais, Tours, France
Department of Pathology, University Hospital Center of Tours
Agnès Carlotti, MD
Department of Pathology, Hospital Cochin-Tarnier, Paris, France
Bruno Giraudeau, PhD
University François Rabelais, Tours, France
INSERM Clinical Investigation Center 202, University Hospital Center of Tours
Loïc Vaillant, MD, PhD
University François Rabelais, Tours, France
Laboratory Ultrasound Signal Instrumentation CNRS FRE 2448, Tours
Department of Dermatology, University Hospital Center of Tours
Laurent Machet, MD, PhD
University François Rabelais, Tours, France
Laboratory Ultrasound Signal Instrumentation CNRS FRE 2448, Tours
Department of Dermatology, University Hospital Center of Tours |
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Keywords: Desmoglein; Drug-induced pemphigus; Idiopathic pemphigus; Immunostaining; Differential diagnosis
Upon completion of this activity, you will be able to:
- define desmoglein and describe the pattern of reactivity seen in drug-induced pemphigus and idiopathic pemphigus when stained with monoclonal antibody 32-2B directed against desmogleins 1 and 3.
- describe the natural history of drug-induced pemphigus beginning with drug exposure and following drug withdrawal.
- list the drugs most frequently implicated in cases of drug-induced pemphigus.
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